High expression of CD59 and CD55 on benign and malignant plasma cells

Thierry Alcindor; Teresa Kimlinger; Thomas E. Witzig

doi:10.1080/10428190500467784

High expression of CD59 and CD55 on benign and malignant plasma cells

Thierry Alcindor, Teresa Kimlinger, Thomas E. Witzig

Hematology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

In summary, our study reveals a relatively high expression of complement regulatory proteins on the surface of plasma cells, which appears to be a constitutive feature of these cells, rather than a specific change induced by a malignant state. Further efforts will aim at establishing a correlation between CD55 and CD59 expression levels and in vitro and in vivo resistance to rituximab.

Original language	English (US)
Pages (from-to)	919-921
Number of pages	3
Journal	Leukemia and Lymphoma
Volume	47
Issue number	5
DOIs	https://doi.org/10.1080/10428190500467784
State	Published - May 1 2006

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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title = "High expression of CD59 and CD55 on benign and malignant plasma cells",

abstract = "In summary, our study reveals a relatively high expression of complement regulatory proteins on the surface of plasma cells, which appears to be a constitutive feature of these cells, rather than a specific change induced by a malignant state. Further efforts will aim at establishing a correlation between CD55 and CD59 expression levels and in vitro and in vivo resistance to rituximab.",

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AB - In summary, our study reveals a relatively high expression of complement regulatory proteins on the surface of plasma cells, which appears to be a constitutive feature of these cells, rather than a specific change induced by a malignant state. Further efforts will aim at establishing a correlation between CD55 and CD59 expression levels and in vitro and in vivo resistance to rituximab.

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