TY - JOUR
T1 - Herpes Zoster-Associated Meningoencephalitis in Patients With Systemic Cancer
AU - HUGHES, BERNADETTE A.
AU - KIMMEL, DAVID W.
AU - AKSAMIT, ALLEN J.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - We reviewed the experience at the Mayo Clinic with neurologic complications related to herpes zoster in patients with systemic cancer. Aside from pain, the most common neurologic complication was zoster-associated meningoencephalitis, which occurred in 9 of 1,125 patients. In these nine patients, the most common underlying malignant lesions were chronic lymphocytic leukemia and lymphoma. All patients in whom meningoencephalitis developed had trigeminal zoster or disseminated zoster. The primary neurologic symptoms were headache, confusion, and somnolence. Nuchal rigidity and fever were uncommon. The response to treatment with acyclovir was generally favorable.
AB - We reviewed the experience at the Mayo Clinic with neurologic complications related to herpes zoster in patients with systemic cancer. Aside from pain, the most common neurologic complication was zoster-associated meningoencephalitis, which occurred in 9 of 1,125 patients. In these nine patients, the most common underlying malignant lesions were chronic lymphocytic leukemia and lymphoma. All patients in whom meningoencephalitis developed had trigeminal zoster or disseminated zoster. The primary neurologic symptoms were headache, confusion, and somnolence. Nuchal rigidity and fever were uncommon. The response to treatment with acyclovir was generally favorable.
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U2 - 10.1016/S0025-6196(12)60600-4
DO - 10.1016/S0025-6196(12)60600-4
M3 - Article
C2 - 8350638
AN - SCOPUS:0027315333
SN - 0025-6196
VL - 68
SP - 652
EP - 655
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 7
ER -