HPS and POPH are uncommon but potentially serious pulmonary consequences of advanced liver disease. The major considerations for liver transplantation posed by these disorders are summarized in Table 4. Remarkably, HPS may completely resolve after OLT; the post-OLT outcome of POPH is less predictable. Both syndromes, under certain conditions, may represent high-risk situations for OLT. The unique opportunity to reverse serious dysfunction in one organ (the lungs) by the successful transplantation of another organ (the liver) is worthy of further clinical investigations.
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine