TY - JOUR
T1 - Hepatopulmonary syndrome and portopulmonary hypertension
T2 - Implications for liver transplantation
AU - Krowka, Michael J.
PY - 2005/12
Y1 - 2005/12
N2 - HPS and POPH are uncommon but potentially serious pulmonary consequences of advanced liver disease. The major considerations for liver transplantation posed by these disorders are summarized in Table 4. Remarkably, HPS may completely resolve after OLT; the post-OLT outcome of POPH is less predictable. Both syndromes, under certain conditions, may represent high-risk situations for OLT. The unique opportunity to reverse serious dysfunction in one organ (the lungs) by the successful transplantation of another organ (the liver) is worthy of further clinical investigations.
AB - HPS and POPH are uncommon but potentially serious pulmonary consequences of advanced liver disease. The major considerations for liver transplantation posed by these disorders are summarized in Table 4. Remarkably, HPS may completely resolve after OLT; the post-OLT outcome of POPH is less predictable. Both syndromes, under certain conditions, may represent high-risk situations for OLT. The unique opportunity to reverse serious dysfunction in one organ (the lungs) by the successful transplantation of another organ (the liver) is worthy of further clinical investigations.
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U2 - 10.1016/j.ccm.2005.06.010
DO - 10.1016/j.ccm.2005.06.010
M3 - Review article
C2 - 16263398
AN - SCOPUS:27644536698
SN - 0272-5231
VL - 26
SP - 587
EP - 597
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
IS - 4
ER -