Hepatopulmonary syndrome - A liver-induced lung vascular disorder

Roberto Rodríguez-Roisin, Michael J. Krowka

Research output: Contribution to journalReview article

381 Scopus citations


The hepatopulmonary syndrome is characterized by defects in oxygenation due to pulmonary abnormalities associated with chronic liver disease. Dyspnea and hypoxemia can be severe and often worsen in the upright position. Gross dilatation of the precapillary and capillary vessels occurs with ventilation-perfusion mismatch. The syndrome usually improves after liver transplantation.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number22
StatePublished - May 29 2008


ASJC Scopus subject areas

  • Medicine(all)

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