Abstract
Background. In this study, we determined the prevalence of hepatitis G virus (HGV) infection in end-stage hepatitis C virus (HCV)-related liver disease and examined the influence of HGV coinfection on the outcome of liver transplantation. Methods. HGV was detected by reverse transcriptase- polymerase chain reaction and Southern blotting in sera drawn from 159 patients who were known to be HCV infected before transplantation. Patients were followed up for a mean of 28.4 months after transplantation. Results. Forty-one (25.3%) patients were HGV positive and the prevalence of HGV infection was similar for different HCV genotypes. Both HGV-positive and - negative groups had similar survival, recurrence rates, inflammatory activity scores, and degree of fibrosis at the time of recurrence. Conclusion. Infection with HGV is common in end-stage HCV-infected patients presenting for liver transplantation. It influences neither the outcome of liver transplantation nor the recurrence of hepatitis in the graft.
Original language | English (US) |
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Pages (from-to) | 786-788 |
Number of pages | 3 |
Journal | Transplantation |
Volume | 64 |
Issue number | 5 |
DOIs | |
State | Published - Sep 15 1997 |
ASJC Scopus subject areas
- Transplantation