Abstract
PURPOSE: To determine if hepatic metastases can be distinguished from cavernous hemangiomas by pattern analysis of magnetic resonance (MR) images obtained prior to and following administration of gadoteridol at standard (0.1 mmol/kg) and triple (0.3 mmol/kg) doses. MATERIALS AND METHODS: Ninety- five patients with proved hepatic metastases (n = 71) or cavernous hemangiomas (n = 24) underwent MR imaging at 16 different institutions. T2- weighted spin-echo and T1-weighted images were obtained before and after gadoteridol administration. Two independent blinded reviewers rated individual features of benignancy versus malignancy on a five-point confidence scale. RESULTS: The most useful diagnostic features, with 100% specificity, were nodular enhancement for hemangiomas and rim enhancement for metastases. Confident (definitely benign or definitely malignant) diagnoses were rendered in 80 of 95 cases (84%), with an accuracy of a confident diagnosis of 96%. CONCLUSION: The pattern of enhancement on T1-weighted images is highly accurate for distinction between hemangiomas and metastases in images obtained with both doses.
Original language | English (US) |
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Pages (from-to) | 49-57 |
Number of pages | 9 |
Journal | Radiology |
Volume | 193 |
Issue number | 1 |
DOIs | |
State | Published - Oct 1994 |
Keywords
- Angioma, gastrointestinal system
- Gadolinium
- Liver neoplasms, diagnosis
- Liver neoplasms, secondary
- Magnetic resonance (MR), pulse sequences
- Magnetic resonance (MR), tissue characterization
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging