Hepatic glucose production estimated by tracer model and deconvolution

Role of endogenous glucose concentration

Antonio Zerman, Claudio Cobelli, Andrea Caumo, Peter Butler, Robert Rizza

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The authors propose a novel, general approach to study the transition from the basal to an euglycemic, hyperinsulinemic state during a dual tracer experiment performed in humans. The approach is based on a physiological model of the glucose-insulin system and deconvolution. The use in the deconvolution algorithm of the calculated endogenous glucose concentration, instead of the measured total glucose concentration, is suggested.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
Place of PublicationPiscataway, NJ, United States
PublisherPubl by IEEE
Pages2289-2290
Number of pages2
Volume13
Editionpt 5
ISBN (Print)0780302168
StatePublished - 1991
Externally publishedYes
EventProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Orlando, FL, USA
Duration: Oct 31 1991Nov 3 1991

Other

OtherProceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityOrlando, FL, USA
Period10/31/9111/3/91

Fingerprint

Deconvolution
Glucose
Physiological models
Insulin
Experiments

ASJC Scopus subject areas

  • Bioengineering

Cite this

Zerman, A., Cobelli, C., Caumo, A., Butler, P., & Rizza, R. (1991). Hepatic glucose production estimated by tracer model and deconvolution: Role of endogenous glucose concentration. In Proceedings of the Annual Conference on Engineering in Medicine and Biology (pt 5 ed., Vol. 13, pp. 2289-2290). Piscataway, NJ, United States: Publ by IEEE.

Hepatic glucose production estimated by tracer model and deconvolution : Role of endogenous glucose concentration. / Zerman, Antonio; Cobelli, Claudio; Caumo, Andrea; Butler, Peter; Rizza, Robert.

Proceedings of the Annual Conference on Engineering in Medicine and Biology. Vol. 13 pt 5. ed. Piscataway, NJ, United States : Publ by IEEE, 1991. p. 2289-2290.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zerman, A, Cobelli, C, Caumo, A, Butler, P & Rizza, R 1991, Hepatic glucose production estimated by tracer model and deconvolution: Role of endogenous glucose concentration. in Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 5 edn, vol. 13, Publ by IEEE, Piscataway, NJ, United States, pp. 2289-2290, Proceedings of the 13th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Orlando, FL, USA, 10/31/91.
Zerman A, Cobelli C, Caumo A, Butler P, Rizza R. Hepatic glucose production estimated by tracer model and deconvolution: Role of endogenous glucose concentration. In Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 5 ed. Vol. 13. Piscataway, NJ, United States: Publ by IEEE. 1991. p. 2289-2290
Zerman, Antonio ; Cobelli, Claudio ; Caumo, Andrea ; Butler, Peter ; Rizza, Robert. / Hepatic glucose production estimated by tracer model and deconvolution : Role of endogenous glucose concentration. Proceedings of the Annual Conference on Engineering in Medicine and Biology. Vol. 13 pt 5. ed. Piscataway, NJ, United States : Publ by IEEE, 1991. pp. 2289-2290
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