Hepatic encephalopathy: A dynamic or static condition

Charmaine A. Stewart, Jane Cerhan

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Hepatic encephalopathy (HE) is a neuropsychiatric disorder associated with portal hypertension. The mechanism of this disorder is still being characterized and the management has relied primarily on lowering the amount of ammonia present in the gastrointestinal tract or reversing liver disease by replacing the diseased liver. It is, however, not established that all the effects of hepatic encephalopathy are reversed by liver transplantation. In this review, we have outlined the mechanisms underlying HE and the pros and cons of reversibility of HE.

Original languageEnglish (US)
Pages (from-to)193-204
Number of pages12
JournalMetabolic Brain Disease
Volume20
Issue number3
DOIs
StatePublished - Sep 1 2005

Keywords

  • Cirrhosis
  • Cognition in liver disease
  • Cognitive dysfunction in liver diseases
  • Decompensated liver disease
  • Hepatic encephalopathy
  • Portosystemic encephalopathy

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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