Abstract
Background: Orthotopic liver transplantation (OLT) models in rats have been investigated in many studies. The reconstruction of hepatic artery is required for reliable OLT and also requires advanced skills. Methods: The hepatic artery reconstructions by a hand-suture technique and a new method using a micro T-tube were investigated in rats with a whole-liver syngeneic graft. Operative time and postoperative patency were compared between the hand-suture and micro T-tube techniques. Results: Our technique using the micro T-tube shortened the operative time of recipient surgery compared with the hand-suture technique and prolonged the operative time for the donor. The patency ratio was maintained at 24 h after OLT with hand suturing but was significantly reduced with the micro T-tube, which had a patency ratio of 0.83 only up to 6 h after OLT. Conclusion: The micro T-tube technique may have potential usefulness in the rat OLT model but requires further modification.
Original language | English (US) |
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Pages (from-to) | 907-914 |
Number of pages | 8 |
Journal | Journal of Surgical Research |
Volume | 178 |
Issue number | 2 |
DOIs | |
State | Published - Dec 2012 |
Keywords
- Hepatic artery
- Liver transplantation
- Microsurgery
- Surgical instruments
ASJC Scopus subject areas
- Surgery