TY - JOUR
T1 - Hemophagocytic Lymphohistiocytosis for the Internist and Other Primary Care Providers
AU - Pai, Tanmayi Srinivas
AU - Stancampiano, Fernando F.
AU - Rivera, Candido
N1 - Publisher Copyright:
© The Author(s) 2021.
PY - 2021
Y1 - 2021
N2 - Hemophagocytic lymphohistiocytosis (HLH) syndrome is a hyperinflammatory state that leads to life-threatening, disproportionate activation of the immune system and may be confused for and concomitantly exist with sepsis. However, its treatment differs from sepsis, requiring early initiation of immunosuppressive treatment. While HLH syndrome is more commonly diagnosed in children, internists and other primary care providers must be familiar with the diagnosis and treatment of adult patients with HLH in the hospital and outpatient setting. In this article, we review the essentials that an internist and other primary care providers managing adult HLH patients should know.
AB - Hemophagocytic lymphohistiocytosis (HLH) syndrome is a hyperinflammatory state that leads to life-threatening, disproportionate activation of the immune system and may be confused for and concomitantly exist with sepsis. However, its treatment differs from sepsis, requiring early initiation of immunosuppressive treatment. While HLH syndrome is more commonly diagnosed in children, internists and other primary care providers must be familiar with the diagnosis and treatment of adult patients with HLH in the hospital and outpatient setting. In this article, we review the essentials that an internist and other primary care providers managing adult HLH patients should know.
KW - HLH
KW - hemophagocytic lymphohistiocytosis
KW - primary care
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U2 - 10.1177/21501327211053756
DO - 10.1177/21501327211053756
M3 - Review article
C2 - 34704505
AN - SCOPUS:85117919725
SN - 2150-1319
VL - 12
JO - Journal of Primary Care and Community Health
JF - Journal of Primary Care and Community Health
ER -