Hemodynamic and autonomic modifications during sleep stages in young hypotensive women

Massimiliano de Zambotti, Naima Covassin, Nicola Cellini, Michela Sarlo, Jacopo Torre, Luciano Stegagno

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

This study examined cardiovascular activity and autonomic involvement during sleep in essential hypotension. We compared young female hypotensives and normotensives using ambulatory blood pressure monitoring, impedance cardiography, and frequency-domain analysis of heart rate variability during a night of polysomnographic recording. Hypotensives, as compared to normotensives, exhibited lower blood pressure, reduced myocardial contractility and reduced sympathovagal balance across the whole night. Both groups exhibited a reduction in cardiovascular involvement from wake to sleep with similar cardiovascular activity during wake and REM. No group difference was observed in sleep architecture suggesting similar sleeping quality in hypotensives and normotensives. The lower blood pressure and reduced myocardial contractility associated with a lower sympathovagal balance in hypotensives, as compared to normotensives, suggest a night-time hypoactivation of the cardiovascular system supporting the hypothesis of impairment in autonomic control in essential hypotension.

Original languageEnglish (US)
Pages (from-to)22-27
Number of pages6
JournalBiological Psychology
Volume91
Issue number1
DOIs
StatePublished - Sep 1 2012

Keywords

  • Cardiovascular
  • Hypotension
  • Low blood pressure
  • Neurovegetative system
  • Sleep

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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