Heart transplantation for radiation-associated end-stage heart failure

Nobuhiro Handa; Christopher G.A. McGregor; Richard C. Daly; Joseph A. Dearani; Brooks S. Edwards; Robert P. Frantz; Lyle J. Olson; Richard J. Rodeheffer

doi:10.1111/j.1432-2277.2000.tb01058.x

Heart transplantation for radiation-associated end-stage heart failure

Nobuhiro Handa, Christopher G.A. McGregor, Richard C. Daly, Joseph A. Dearani, Brooks S. Edwards, Robert P. Frantz, Lyle J. Olson, Richard J. Rodeheffer

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Radiation-induced heart disease is an increasingly recognized late sequela of mediastinal radiation therapy for malignant neoplasms. We report four cases of heart transplantation for end-stage heart failure induced by mediastinal radiation therapy. Short-term and intermediate-term results are excellent with all four patients currently surviving a mean of 48 months after transplantation. Neither a second malignancy nor recurrence of the primary malignancy has been observed to date. The early results of heart transplantation for end-stage, radiation-induced heart disease are encouraging.

Original language	English (US)
Pages (from-to)	162-165
Number of pages	4
Journal	Transplant International
Volume	13
Issue number	2
DOIs	https://doi.org/10.1111/j.1432-2277.2000.tb01058.x
State	Published - Mar 2000

Keywords

Heart transplantation
Radiation-induced heart disease

ASJC Scopus subject areas

Transplantation

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title = "Heart transplantation for radiation-associated end-stage heart failure",

abstract = "Radiation-induced heart disease is an increasingly recognized late sequela of mediastinal radiation therapy for malignant neoplasms. We report four cases of heart transplantation for end-stage heart failure induced by mediastinal radiation therapy. Short-term and intermediate-term results are excellent with all four patients currently surviving a mean of 48 months after transplantation. Neither a second malignancy nor recurrence of the primary malignancy has been observed to date. The early results of heart transplantation for end-stage, radiation-induced heart disease are encouraging.",

keywords = "Heart transplantation, Radiation-induced heart disease",

author = "Nobuhiro Handa and McGregor, {Christopher G.A.} and Daly, {Richard C.} and Dearani, {Joseph A.} and Edwards, {Brooks S.} and Frantz, {Robert P.} and Olson, {Lyle J.} and Rodeheffer, {Richard J.}",

year = "2000",

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T1 - Heart transplantation for radiation-associated end-stage heart failure

AU - Handa, Nobuhiro

AU - McGregor, Christopher G.A.

AU - Daly, Richard C.

AU - Dearani, Joseph A.

AU - Edwards, Brooks S.

AU - Frantz, Robert P.

AU - Olson, Lyle J.

AU - Rodeheffer, Richard J.

PY - 2000/3

Y1 - 2000/3

N2 - Radiation-induced heart disease is an increasingly recognized late sequela of mediastinal radiation therapy for malignant neoplasms. We report four cases of heart transplantation for end-stage heart failure induced by mediastinal radiation therapy. Short-term and intermediate-term results are excellent with all four patients currently surviving a mean of 48 months after transplantation. Neither a second malignancy nor recurrence of the primary malignancy has been observed to date. The early results of heart transplantation for end-stage, radiation-induced heart disease are encouraging.

AB - Radiation-induced heart disease is an increasingly recognized late sequela of mediastinal radiation therapy for malignant neoplasms. We report four cases of heart transplantation for end-stage heart failure induced by mediastinal radiation therapy. Short-term and intermediate-term results are excellent with all four patients currently surviving a mean of 48 months after transplantation. Neither a second malignancy nor recurrence of the primary malignancy has been observed to date. The early results of heart transplantation for end-stage, radiation-induced heart disease are encouraging.

KW - Heart transplantation

KW - Radiation-induced heart disease

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Heart transplantation for radiation-associated end-stage heart failure

Abstract

Keywords

ASJC Scopus subject areas

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