Health-related quality of life in children and adolescents with juvenile localized scleroderma

Nicole M. Orzechowski, Dawn M. Davis, Thomas Mason, Cynthia Crowson, Ann M. Reed

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Objectives. To examine the health-related quality of life (HRQOL) of children with juvenile localized scleroderma (JLS) and to compare them with patients with atopic dermatitis (AD) and healthy controls. Methods. The cohorts were identified through a diagnostic index and were seen between January 1996 and December 2006. We identified 81 JLS patients to whom we age- and sex-matched 75 AD patients and 75 healthy controls. All patients were mailed a survey containing the English-language version of the German Revised Children's Quality of Life Questionnaire (KINDL) and the Children's Dermatology Life Quality Index (CDLQI). Linear regression models, adjusted for age and sex, examined differences in the KINDL and CDLQI scores. Results. Survey completion rates in the JLS, AD and healthy control groups were 40, 28 and 44%, respectively. There was no difference in KINDL scores between JLS vs AD (73 vs 74, P = 0.3) and JLS vs healthy controls (73 vs 74, P = 0.8). However, CDLQI scores showed some impairment in HRQOL in JLS patients as compared with a healthy reference population, but not to the degree seen in AD (2 vs 4, P = 0.05). An exploratory analysis showed that HRQOL did not differ among the types of JLS with either measure. Conclusion. JLS patients have some impairment in skin disease-specific HRQOL when compared with a healthy reference population, but not as severe as that seen in AD patients. Overall HRQOL in this JLS cohort was as good as healthy controls, a reassuring finding for patients, families and healthcare providers.

Original languageEnglish (US)
Pages (from-to)670-672
Number of pages3
JournalRheumatology
Volume48
Issue number6
DOIs
StatePublished - 2009

Fingerprint

Localized Scleroderma
Quality of Life
Atopic Dermatitis
Dermatology
Linear Models
Juvenile-onset scleroderma
Skin Diseases
Sex Characteristics
Health Personnel
Population
Language
Control Groups

Keywords

  • Health-related quality of life
  • Juvenile localized scleroderma
  • Morphoea

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

Cite this

Health-related quality of life in children and adolescents with juvenile localized scleroderma. / Orzechowski, Nicole M.; Davis, Dawn M.; Mason, Thomas; Crowson, Cynthia; Reed, Ann M.

In: Rheumatology, Vol. 48, No. 6, 2009, p. 670-672.

Research output: Contribution to journalArticle

Orzechowski, Nicole M. ; Davis, Dawn M. ; Mason, Thomas ; Crowson, Cynthia ; Reed, Ann M. / Health-related quality of life in children and adolescents with juvenile localized scleroderma. In: Rheumatology. 2009 ; Vol. 48, No. 6. pp. 670-672.
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