TY - JOUR
T1 - Health Care Utilization in Systemic Lupus Erythematosus in the Community
T2 - The Lupus Midwest Network
AU - Chevet, Baptiste
AU - Figueroa-Parra, Gabriel
AU - Valenzuela-Almada, Maria O.
AU - Hocaoglu, Mehmet
AU - Vallejo, Sebastian
AU - Osei-Onomah, Shirley Ann
AU - Giblon, Rachel E.
AU - Dabit, Jesse Y.
AU - Chamberlain, Alanna
AU - Cornec, Divi
AU - Greenlund, Kurt J.
AU - Barbour, Kamil E.
AU - Crowson, Cynthia S.
AU - Duarte-García, Alí
N1 - Funding Information:
A.D.-G. is supported by the Rheumatology Research Foundation Scientist Development Award and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery.
Funding Information:
This study used the resources of the Rochester Epidemiology Project (REP) medical records–linkage system, which is supported by the National Institute on Aging (AG 058738), by the Mayo Clinic Research Committee, and by fees paid annually by REP users. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the CDC or the National Institutes of Health.
Funding Information:
The Lupus Midwest Network (LUMEN) project is supported by the Centers for Disease Control and Prevention (CDC) of the US Department of Health and Human Services (HHS) under grant U01 DP006491 as part of a financial assistance award totaling $1,750,000 with 100% funded by CDC/HHS.
Publisher Copyright:
© Wolters Kluwer Health, Inc.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Objective The aim of this study was to determine inpatient health care utilization in an incident cohort of patients with systemic lupus erythematosus (SLE) compared with the general population. Methods This was a population-based cohort study in the upper Midwest, United States. We included patients fulfilling the European League Against Rheumatism/American College of Rheumatology SLE classification criteria between 1995 and 2018. They were 1:1 age-, sex-, county-matched with individuals without SLE. All hospital admissions and emergency department (ED) visits were electronically retrieved for 1995-2020. Rates for hospital admission, length of stay, readmission, ED visits, and discharge destination were compared between groups. Results Three hundred forty-one patients with SLE and 341 comparators without SLE were included (mean age, 48.6 years at diagnosis; 79.2% female). Rates of hospitalization for patients with SLE and comparators were 29.8 and 9.9 per 100 person-years, respectively. These differences were present across sexes and age groups. Hospitalization rates were higher in patients with SLE after diagnosis and remained higher than comparators for the first 15 years of the disease. Patients with SLE were more likely than comparators to visit the ED (hazard ratio, 2.71; 95% confidence interval, 2.05-3.59). Readmission rates (32% vs. 21%, p = 0.017) were higher in patients with SLE. Length of stay and discharge destination were similar between both groups. Conclusion Patients with SLE were more likely to be hospitalized and to visit the ED than individuals without SLE, highlighting important inpatient care needs. Increased hospitalization rates were observed in both male and female patients and all age groups.
AB - Objective The aim of this study was to determine inpatient health care utilization in an incident cohort of patients with systemic lupus erythematosus (SLE) compared with the general population. Methods This was a population-based cohort study in the upper Midwest, United States. We included patients fulfilling the European League Against Rheumatism/American College of Rheumatology SLE classification criteria between 1995 and 2018. They were 1:1 age-, sex-, county-matched with individuals without SLE. All hospital admissions and emergency department (ED) visits were electronically retrieved for 1995-2020. Rates for hospital admission, length of stay, readmission, ED visits, and discharge destination were compared between groups. Results Three hundred forty-one patients with SLE and 341 comparators without SLE were included (mean age, 48.6 years at diagnosis; 79.2% female). Rates of hospitalization for patients with SLE and comparators were 29.8 and 9.9 per 100 person-years, respectively. These differences were present across sexes and age groups. Hospitalization rates were higher in patients with SLE after diagnosis and remained higher than comparators for the first 15 years of the disease. Patients with SLE were more likely than comparators to visit the ED (hazard ratio, 2.71; 95% confidence interval, 2.05-3.59). Readmission rates (32% vs. 21%, p = 0.017) were higher in patients with SLE. Length of stay and discharge destination were similar between both groups. Conclusion Patients with SLE were more likely to be hospitalized and to visit the ED than individuals without SLE, highlighting important inpatient care needs. Increased hospitalization rates were observed in both male and female patients and all age groups.
KW - epidemiology
KW - health care utilization
KW - hospitalization
KW - incidence
KW - systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=85144595491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85144595491&partnerID=8YFLogxK
U2 - 10.1097/RHU.0000000000001899
DO - 10.1097/RHU.0000000000001899
M3 - Article
C2 - 36251449
AN - SCOPUS:85144595491
VL - 29
SP - 29
EP - 35
JO - Journal of Clinical Rheumatology
JF - Journal of Clinical Rheumatology
SN - 1076-1608
IS - 1
ER -