Abstract
Approximately 700 hemoglobin variants have been reported, causing a variety of clinical manifestations, with the majority being clinically silent. We report a new hemoglobin variant, Hb Cook, that was found in combination with Hb E in a child of Thai origin. DNA sequencing of the β- globin gene showed that the mutation is AAA→ACA in codon 132, corresponding to β132 (H10)Lys→Thr.
Original language | English (US) |
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Pages (from-to) | 371-376 |
Number of pages | 6 |
Journal | Hemoglobin |
Volume | 20 |
Issue number | 4 |
DOIs | |
State | Published - 1996 |
ASJC Scopus subject areas
- Hematology
- Clinical Biochemistry
- Genetics(clinical)
- Biochemistry, medical