Harnessing big data for precision medicine: Infrastructures and applications

Kun Hsing Yu, Steven Hart, Rachel Goldfeder, Qiangfeng Cliff Zhang, Stephen C.J. Parker, Michael Snyder

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Precision medicine is a health management approach that accounts for individual differences in genetic backgrounds and environmental exposures. With the recent advancements in high-throughput omics profiling technologies, collections of large study cohorts, and the developments of data mining algorithms, big data in biomedicine is expected to provide novel insights into health and disease states, which can be translated into personalized disease prevention and treatment plans. However, petabytes of biomedical data generated by multiple measurement modalities poses a significant challenge for data analysis, integration, storage, and result interpretation. In addition, patient privacy preservation, coordination between participating medical centers and data analysis working groups, as well as discrepancies in data sharing policies remain important topics of discussion. In this workshop, we invite experts in omics integration, biobank research, and data management to share their perspectives on leveraging big data to enable precision medicine.

Original languageEnglish (US)
Title of host publicationPACIFIC SYMPOSIUM ON BIOCOMPUTING 2017
EditorsRuss B. Altman, Tiffany Murray, Teri E. Klein, A. Keith Dunker, Marylyn D. Ritchie, Lawrence Hunter
PublisherWorld Scientific Publishing Co. Pte Ltd
Number of pages5
ISBN (Print)9789813207813
StatePublished - Jan 1 2017
Event22nd Pacific Symposium on Biocomputing, PSB 2017 - Kohala Coast, United States
Duration: Jan 4 2017Jan 8 2017


Other22nd Pacific Symposium on Biocomputing, PSB 2017
CountryUnited States
CityKohala Coast

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computational Theory and Mathematics
  • Medicine(all)

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    Yu, K. H., Hart, S., Goldfeder, R., Zhang, Q. C., Parker, S. C. J., & Snyder, M. (2017). Harnessing big data for precision medicine: Infrastructures and applications. In R. B. Altman, T. Murray, T. E. Klein, A. K. Dunker, M. D. Ritchie, & L. Hunter (Eds.), PACIFIC SYMPOSIUM ON BIOCOMPUTING 2017 (212679 ed., pp. 635-639). World Scientific Publishing Co. Pte Ltd. https://doi.org/10.1142/9789813207813_0058