Hand transplantation

Brian T. Carlsen, Hatem Amer, Steven Lawrence Moran

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Since the first hand transplantation was performed more than a decade ago, much has been learned about the risks and benefits of this procedure. It is now clear that the procedure is technically possible and the transplanted hand will survive with appropriate immunosuppression. While controversy remains, there is increasing acceptance of the procedure in appropriately selected patients. Technically, the procedure is similar to replantation of an amputated hand with some important distinctions: no zone of injury, more skin for coverage, and important challenges with recipient and donor muscle tensioning. Acute rejection is common but manageable with steroids and modification of immunosuppressive therapy. Quantifying function is challenging, as no perfect measure exists. However, outcome measures assessed are quite favorable but require an intense hand therapy program. There are unique psychosocial considerations in this patient population, and careful patient selection is critical to a successful outcome.

Original languageEnglish (US)
Pages (from-to)331-335
Number of pages5
JournalCurrent Orthopaedic Practice
Volume23
Issue number4
DOIs
StatePublished - Jul 2012

Fingerprint

Hand Transplantation
Hand
Replantation
Immunosuppressive Agents
Immunosuppression
Patient Selection
Steroids
Outcome Assessment (Health Care)
Tissue Donors
Muscles
Skin
Wounds and Injuries
Therapeutics
Population

Keywords

  • Amputation
  • Composite tissue allotransplantation
  • Hand transplantation
  • Vascularized composite allotransplantation

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Hand transplantation. / Carlsen, Brian T.; Amer, Hatem; Moran, Steven Lawrence.

In: Current Orthopaedic Practice, Vol. 23, No. 4, 07.2012, p. 331-335.

Research output: Contribution to journalArticle

Carlsen, Brian T. ; Amer, Hatem ; Moran, Steven Lawrence. / Hand transplantation. In: Current Orthopaedic Practice. 2012 ; Vol. 23, No. 4. pp. 331-335.
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