Hamartomas and malformations of the liver

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Hamartomas and malformations of the liver are rare and can lead to diagnostic challenges. Most present as mass lesions that can mimic true neoplasms of the liver on imaging and sometimes on histology, one example being focal nodular hyperplasia. The primary cell type in the hamartomas and malformations can be biliary, vascular, or hepatic. Biliary lesions include bile duct hamartomas and simple liver cysts. Other cystic malformations include the ciliated hepatic foregut cysts and mesothelial cysts. Vascular malformations include telangiectasias, arteriovenous malformations, and hereditary lymphedema. Malformations composed primarily of hepatocytes include accessory lobes and focal nodular hyperplasia. All of these entities are discussed, with a focus on the diagnostic histological findings.

Original languageEnglish (US)
Pages (from-to)39-47
Number of pages9
JournalSeminars in Diagnostic Pathology
Volume36
Issue number1
DOIs
StatePublished - Jan 1 2019

Fingerprint

Hamartoma
Focal Nodular Hyperplasia
Cysts
Liver
Telangiectasis
Vascular Malformations
Lymphedema
Arteriovenous Malformations
Liver Neoplasms
Bile Ducts
Blood Vessels
Hepatocytes
Histology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Hamartomas and malformations of the liver. / Torbenson, Michael.

In: Seminars in Diagnostic Pathology, Vol. 36, No. 1, 01.01.2019, p. 39-47.

Research output: Contribution to journalReview article

@article{5c997d8c03684604a484546f6c053361,
title = "Hamartomas and malformations of the liver",
abstract = "Hamartomas and malformations of the liver are rare and can lead to diagnostic challenges. Most present as mass lesions that can mimic true neoplasms of the liver on imaging and sometimes on histology, one example being focal nodular hyperplasia. The primary cell type in the hamartomas and malformations can be biliary, vascular, or hepatic. Biliary lesions include bile duct hamartomas and simple liver cysts. Other cystic malformations include the ciliated hepatic foregut cysts and mesothelial cysts. Vascular malformations include telangiectasias, arteriovenous malformations, and hereditary lymphedema. Malformations composed primarily of hepatocytes include accessory lobes and focal nodular hyperplasia. All of these entities are discussed, with a focus on the diagnostic histological findings.",
author = "Michael Torbenson",
year = "2019",
month = "1",
day = "1",
doi = "10.1053/j.semdp.2018.11.005",
language = "English (US)",
volume = "36",
pages = "39--47",
journal = "Seminars in Diagnostic Pathology",
issn = "0740-2570",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Hamartomas and malformations of the liver

AU - Torbenson, Michael

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Hamartomas and malformations of the liver are rare and can lead to diagnostic challenges. Most present as mass lesions that can mimic true neoplasms of the liver on imaging and sometimes on histology, one example being focal nodular hyperplasia. The primary cell type in the hamartomas and malformations can be biliary, vascular, or hepatic. Biliary lesions include bile duct hamartomas and simple liver cysts. Other cystic malformations include the ciliated hepatic foregut cysts and mesothelial cysts. Vascular malformations include telangiectasias, arteriovenous malformations, and hereditary lymphedema. Malformations composed primarily of hepatocytes include accessory lobes and focal nodular hyperplasia. All of these entities are discussed, with a focus on the diagnostic histological findings.

AB - Hamartomas and malformations of the liver are rare and can lead to diagnostic challenges. Most present as mass lesions that can mimic true neoplasms of the liver on imaging and sometimes on histology, one example being focal nodular hyperplasia. The primary cell type in the hamartomas and malformations can be biliary, vascular, or hepatic. Biliary lesions include bile duct hamartomas and simple liver cysts. Other cystic malformations include the ciliated hepatic foregut cysts and mesothelial cysts. Vascular malformations include telangiectasias, arteriovenous malformations, and hereditary lymphedema. Malformations composed primarily of hepatocytes include accessory lobes and focal nodular hyperplasia. All of these entities are discussed, with a focus on the diagnostic histological findings.

UR - http://www.scopus.com/inward/record.url?scp=85058631364&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058631364&partnerID=8YFLogxK

U2 - 10.1053/j.semdp.2018.11.005

DO - 10.1053/j.semdp.2018.11.005

M3 - Review article

C2 - 30579648

AN - SCOPUS:85058631364

VL - 36

SP - 39

EP - 47

JO - Seminars in Diagnostic Pathology

JF - Seminars in Diagnostic Pathology

SN - 0740-2570

IS - 1

ER -