Abstract
Hallucinogens were competitive antagonists of histamine at the H1-receptor of cultured mouse neuroblastoma cells. Their rank order of potency at this receptor was similar to that for their potency at eliciting subjective effects in vivo. Comparison with studies of other receptors, however, suggests that no single model of drug-receptor interaction adequately accounts for the known subjective effects of these compounds.
Original language | English (US) |
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Pages (from-to) | 260-264 |
Number of pages | 5 |
Journal | European Journal of Pharmacology |
Volume | 56 |
Issue number | 3 |
DOIs | |
State | Published - Jun 15 1979 |
Keywords
- Cyclic GMP
- H-receptor
- Hallucinogen
- Histamine
ASJC Scopus subject areas
- Pharmacology