Graves' ophthalmopathy

Rebecca S. Bahn

Research output: Contribution to journalReview article

589 Scopus citations

Abstract

This article reviews the mechanisms that lead to the development of Graves' ophthalmopathy. A central feature in its development is autoimmunity that involves not only T cells, B cells, and macrophages but also fibroblasts and adipose tissue within the orbit. Intraorbital cytokine-mediated inflammation also has a prominent role. These recent findings suggest new ways of treating this debilitating disease.

Original languageEnglish (US)
Pages (from-to)726-738+774
JournalNew England Journal of Medicine
Volume362
Issue number8
DOIs
StatePublished - Feb 25 2010

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ASJC Scopus subject areas

  • Medicine(all)

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