Graves' ophthalmopathy

Rebecca S. Bahn

Research output: Contribution to journalArticle

526 Citations (Scopus)

Abstract

This article reviews the mechanisms that lead to the development of Graves' ophthalmopathy. A central feature in its development is autoimmunity that involves not only T cells, B cells, and macrophages but also fibroblasts and adipose tissue within the orbit. Intraorbital cytokine-mediated inflammation also has a prominent role. These recent findings suggest new ways of treating this debilitating disease.

Original languageEnglish (US)
JournalNew England Journal of Medicine
Volume362
Issue number8
DOIs
StatePublished - Feb 25 2010

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Graves Ophthalmopathy
Orbit
Autoimmunity
Adipose Tissue
B-Lymphocytes
Fibroblasts
Macrophages
Cytokines
Inflammation
T-Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Graves' ophthalmopathy. / Bahn, Rebecca S.

In: New England Journal of Medicine, Vol. 362, No. 8, 25.02.2010.

Research output: Contribution to journalArticle

Bahn, Rebecca S. / Graves' ophthalmopathy. In: New England Journal of Medicine. 2010 ; Vol. 362, No. 8.
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