Granulocytic sarcoma of the small intestine preceding acute myelomonocytic leukemia with abnormal eosinophils and inv(16)

Stephen J Russell, F. J. Giles, D. S. Thompson, D. J. Scanlon, Helen Walker, J. D M Richards

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We report a case of preleukemic granulocytic sarcoma of the small intestine preceding the development of acute myelomonocytic leukemia with abnormal eosinophils and inversion of chromosome 16, inv(16)(p13q22). A literature review suggests that this is a recurring cytogenetic-clinicopathologic association and carries a favorable prognosis, especially if treated aggressively with antileukemic therapy at the time of diagnosis.

Original languageEnglish (US)
Pages (from-to)231-235
Number of pages5
JournalCancer Genetics and Cytogenetics
Volume35
Issue number2
DOIs
StatePublished - Oct 15 1988
Externally publishedYes

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Leukemia, Myelomonocytic, Acute
Myeloid Sarcoma
Chromosomes, Human, Pair 16
Eosinophils
Cytogenetics
Small Intestine
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Granulocytic sarcoma of the small intestine preceding acute myelomonocytic leukemia with abnormal eosinophils and inv(16). / Russell, Stephen J; Giles, F. J.; Thompson, D. S.; Scanlon, D. J.; Walker, Helen; Richards, J. D M.

In: Cancer Genetics and Cytogenetics, Vol. 35, No. 2, 15.10.1988, p. 231-235.

Research output: Contribution to journalArticle

Russell, Stephen J ; Giles, F. J. ; Thompson, D. S. ; Scanlon, D. J. ; Walker, Helen ; Richards, J. D M. / Granulocytic sarcoma of the small intestine preceding acute myelomonocytic leukemia with abnormal eosinophils and inv(16). In: Cancer Genetics and Cytogenetics. 1988 ; Vol. 35, No. 2. pp. 231-235.
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