Going viral: Fusiform vertebrobasilar and internal carotid aneurysms with varicella angiitis and common variable immunodeficiency - Case report

Wilson P. Daugherty, Michelle J. Clarke, Harry J. Cloft, Giuseppe L. Lanzino

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Intracranial aneurysms in the pediatric population are relatively rare entities. Immunocompromised patients (often from HIV/AIDS or pharmacological immunosuppression) represent a significant fraction of children with cerebral aneurysms. One proposed mechanism of aneurysm formation in these patients is from direct infection of the affected arteries. In this study, the authors report on a case of a 14-year-old girl with common variable immuno-deficiency with T-cell dysfunction and a CSF polymerase chain reaction test positive for varicella-zoster virus who underwent evaluation for carotid and basilar artery fusiform aneurysms.

Original languageEnglish (US)
Pages (from-to)528-531
Number of pages4
JournalJournal of Neurosurgery: Pediatrics
Volume4
Issue number6
DOIs
StatePublished - Dec 1 2009

Keywords

  • Angiitis
  • Cerebral aneurysm
  • Common variable immunodeficiency
  • Stroke
  • Varicella

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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