Abstract
An association between mutations in the glucocerebrosidase (GBA) gene and Parkinson disease (PD) was recently reported in Ashkenazi Jews. The authors screened a series of 311 Norwegian patients with PD and 474 controls for 2 common functional mutations of the GBA protein, N370S and L444P. Seven patients (2.3%) and 8 controls (1.7%) carried a mutant GBA allele (p = 0.58). This study does not indicate increased susceptibility to PD in GBA mutations carriers in Norway.
Original language | English (US) |
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Pages (from-to) | 415-417 |
Number of pages | 3 |
Journal | Neurology |
Volume | 66 |
Issue number | 3 |
DOIs | |
State | Published - Feb 2006 |
ASJC Scopus subject areas
- Clinical Neurology