Global endometrial ablation for menorrhagia in women with bleeding disorders

Sherif A. El-Nashar, Matthew R. Hopkins, Simone S. Feitoza, Rajiv K. Pruthi, Sunni A. Barnes, John B. Gebhart, William Arthur Cliby, Abimbola O. Famuyide

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia. METHODS: A records-linkage system was used to construct a retrospective cohort of 41 women with bleeding disorders (coagulopathy) and a reference group of 111 randomly selected women without bleeding disorders from a pool of 943 women who underwent global endometrial ablation (with thermal balloon ablation technology or bipolar radiofrequency ablation technology) for menorrhagia at Mayo Clinic (Rochester, Minnesota) from January 1995 through December 2005. Demographic data, type of global endometrial ablation therapy and reablation, and hysterectomy data were extracted from the database. RESULTS: There was no significant difference in baseline age, parity, body mass index, uterine size, type of global endometrial ablation therapy, or duration of follow-up between the groups. Two women (5%) in the coagulopathy group had hysterectomy or reablation, compared with 8 (7%) in the reference group (Fisher exact test, P=.728). A Kaplan-Meier plot showed no difference in the time to treatment failure between the groups (log-rank test, P=.534). Procedural-related complications were generally minor and infrequent (9 of 152 [6%]). Complications were equally distributed in the coagulopathy (4 of 41) and reference groups (6 of 111) (Fisher exact test, P=.267). CONCLUSION: Global endometrial ablation is an effective treatment choice for women with coagulopathy presenting with menorrhagia.

Original languageEnglish (US)
Pages (from-to)1381-1387
Number of pages7
JournalObstetrics and Gynecology
Volume109
Issue number6
DOIs
StatePublished - Jun 2007

Fingerprint

Endometrial Ablation Techniques
Menorrhagia
Hemorrhage
Hysterectomy
Technology
Parity
Treatment Failure
Body Mass Index
Therapeutics
Hot Temperature
Demography
Databases

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

El-Nashar, S. A., Hopkins, M. R., Feitoza, S. S., Pruthi, R. K., Barnes, S. A., Gebhart, J. B., ... Famuyide, A. O. (2007). Global endometrial ablation for menorrhagia in women with bleeding disorders. Obstetrics and Gynecology, 109(6), 1381-1387. https://doi.org/10.1097/01.AOG.0000265805.76453.33

Global endometrial ablation for menorrhagia in women with bleeding disorders. / El-Nashar, Sherif A.; Hopkins, Matthew R.; Feitoza, Simone S.; Pruthi, Rajiv K.; Barnes, Sunni A.; Gebhart, John B.; Cliby, William Arthur; Famuyide, Abimbola O.

In: Obstetrics and Gynecology, Vol. 109, No. 6, 06.2007, p. 1381-1387.

Research output: Contribution to journalArticle

El-Nashar, SA, Hopkins, MR, Feitoza, SS, Pruthi, RK, Barnes, SA, Gebhart, JB, Cliby, WA & Famuyide, AO 2007, 'Global endometrial ablation for menorrhagia in women with bleeding disorders', Obstetrics and Gynecology, vol. 109, no. 6, pp. 1381-1387. https://doi.org/10.1097/01.AOG.0000265805.76453.33
El-Nashar SA, Hopkins MR, Feitoza SS, Pruthi RK, Barnes SA, Gebhart JB et al. Global endometrial ablation for menorrhagia in women with bleeding disorders. Obstetrics and Gynecology. 2007 Jun;109(6):1381-1387. https://doi.org/10.1097/01.AOG.0000265805.76453.33
El-Nashar, Sherif A. ; Hopkins, Matthew R. ; Feitoza, Simone S. ; Pruthi, Rajiv K. ; Barnes, Sunni A. ; Gebhart, John B. ; Cliby, William Arthur ; Famuyide, Abimbola O. / Global endometrial ablation for menorrhagia in women with bleeding disorders. In: Obstetrics and Gynecology. 2007 ; Vol. 109, No. 6. pp. 1381-1387.
@article{fe65338c4677478585e01fcf3d7e87e3,
title = "Global endometrial ablation for menorrhagia in women with bleeding disorders",
abstract = "OBJECTIVE: To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia. METHODS: A records-linkage system was used to construct a retrospective cohort of 41 women with bleeding disorders (coagulopathy) and a reference group of 111 randomly selected women without bleeding disorders from a pool of 943 women who underwent global endometrial ablation (with thermal balloon ablation technology or bipolar radiofrequency ablation technology) for menorrhagia at Mayo Clinic (Rochester, Minnesota) from January 1995 through December 2005. Demographic data, type of global endometrial ablation therapy and reablation, and hysterectomy data were extracted from the database. RESULTS: There was no significant difference in baseline age, parity, body mass index, uterine size, type of global endometrial ablation therapy, or duration of follow-up between the groups. Two women (5{\%}) in the coagulopathy group had hysterectomy or reablation, compared with 8 (7{\%}) in the reference group (Fisher exact test, P=.728). A Kaplan-Meier plot showed no difference in the time to treatment failure between the groups (log-rank test, P=.534). Procedural-related complications were generally minor and infrequent (9 of 152 [6{\%}]). Complications were equally distributed in the coagulopathy (4 of 41) and reference groups (6 of 111) (Fisher exact test, P=.267). CONCLUSION: Global endometrial ablation is an effective treatment choice for women with coagulopathy presenting with menorrhagia.",
author = "El-Nashar, {Sherif A.} and Hopkins, {Matthew R.} and Feitoza, {Simone S.} and Pruthi, {Rajiv K.} and Barnes, {Sunni A.} and Gebhart, {John B.} and Cliby, {William Arthur} and Famuyide, {Abimbola O.}",
year = "2007",
month = "6",
doi = "10.1097/01.AOG.0000265805.76453.33",
language = "English (US)",
volume = "109",
pages = "1381--1387",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Global endometrial ablation for menorrhagia in women with bleeding disorders

AU - El-Nashar, Sherif A.

AU - Hopkins, Matthew R.

AU - Feitoza, Simone S.

AU - Pruthi, Rajiv K.

AU - Barnes, Sunni A.

AU - Gebhart, John B.

AU - Cliby, William Arthur

AU - Famuyide, Abimbola O.

PY - 2007/6

Y1 - 2007/6

N2 - OBJECTIVE: To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia. METHODS: A records-linkage system was used to construct a retrospective cohort of 41 women with bleeding disorders (coagulopathy) and a reference group of 111 randomly selected women without bleeding disorders from a pool of 943 women who underwent global endometrial ablation (with thermal balloon ablation technology or bipolar radiofrequency ablation technology) for menorrhagia at Mayo Clinic (Rochester, Minnesota) from January 1995 through December 2005. Demographic data, type of global endometrial ablation therapy and reablation, and hysterectomy data were extracted from the database. RESULTS: There was no significant difference in baseline age, parity, body mass index, uterine size, type of global endometrial ablation therapy, or duration of follow-up between the groups. Two women (5%) in the coagulopathy group had hysterectomy or reablation, compared with 8 (7%) in the reference group (Fisher exact test, P=.728). A Kaplan-Meier plot showed no difference in the time to treatment failure between the groups (log-rank test, P=.534). Procedural-related complications were generally minor and infrequent (9 of 152 [6%]). Complications were equally distributed in the coagulopathy (4 of 41) and reference groups (6 of 111) (Fisher exact test, P=.267). CONCLUSION: Global endometrial ablation is an effective treatment choice for women with coagulopathy presenting with menorrhagia.

AB - OBJECTIVE: To evaluate the efficacy of global endometrial ablation in women with bleeding disorders who presented with menorrhagia. METHODS: A records-linkage system was used to construct a retrospective cohort of 41 women with bleeding disorders (coagulopathy) and a reference group of 111 randomly selected women without bleeding disorders from a pool of 943 women who underwent global endometrial ablation (with thermal balloon ablation technology or bipolar radiofrequency ablation technology) for menorrhagia at Mayo Clinic (Rochester, Minnesota) from January 1995 through December 2005. Demographic data, type of global endometrial ablation therapy and reablation, and hysterectomy data were extracted from the database. RESULTS: There was no significant difference in baseline age, parity, body mass index, uterine size, type of global endometrial ablation therapy, or duration of follow-up between the groups. Two women (5%) in the coagulopathy group had hysterectomy or reablation, compared with 8 (7%) in the reference group (Fisher exact test, P=.728). A Kaplan-Meier plot showed no difference in the time to treatment failure between the groups (log-rank test, P=.534). Procedural-related complications were generally minor and infrequent (9 of 152 [6%]). Complications were equally distributed in the coagulopathy (4 of 41) and reference groups (6 of 111) (Fisher exact test, P=.267). CONCLUSION: Global endometrial ablation is an effective treatment choice for women with coagulopathy presenting with menorrhagia.

UR - http://www.scopus.com/inward/record.url?scp=34249897216&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249897216&partnerID=8YFLogxK

U2 - 10.1097/01.AOG.0000265805.76453.33

DO - 10.1097/01.AOG.0000265805.76453.33

M3 - Article

C2 - 17540811

AN - SCOPUS:34249897216

VL - 109

SP - 1381

EP - 1387

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 6

ER -