Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET

Jerry J. Shih, Harley Kornblum, D. Alan Shewmon

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Pyridoxine dependency often presents with intractable seizures in neonates and infants. We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process.

Original languageEnglish (US)
Pages (from-to)824-826
Number of pages3
JournalNeurology
Volume47
Issue number3
DOIs
StatePublished - Sep 1996

ASJC Scopus subject areas

  • Clinical Neurology

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