Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET

Jerry J. Shih; Harley Kornblum; D. Alan Shewmon

doi:10.1212/WNL.47.3.824

Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET

Jerry J. Shih, Harley Kornblum, D. Alan Shewmon

Neurology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Pyridoxine dependency often presents with intractable seizures in neonates and infants. We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process.

Original language	English (US)
Pages (from-to)	824-826
Number of pages	3
Journal	Neurology
Volume	47
Issue number	3
DOIs	https://doi.org/10.1212/WNL.47.3.824
State	Published - Sep 1996

ASJC Scopus subject areas

Clinical Neurology

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10.1212/WNL.47.3.824

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title = "Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET",

abstract = "Pyridoxine dependency often presents with intractable seizures in neonates and infants. We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process.",

author = "Shih, {Jerry J.} and Harley Kornblum and Shewmon, {D. Alan}",

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AB - Pyridoxine dependency often presents with intractable seizures in neonates and infants. We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process.

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Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET

Abstract

ASJC Scopus subject areas

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