Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women

Latha Kadalayil, Sofia Khan, Heli Nevanlinna, Peter A. Fasching, Fergus J Couch, John L. Hopper, Jianjun Liu, Tom Maishman, Lorraine Durcan, Sue Gerty, Carl Blomqvist, Brigitte Rack, Wolfgang Janni, Andrew Collins, Diana Eccles, William Tapper

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Genetic variance can influence breast cancer prognosis. Here, the authors conduct a meta-analysis to explore genetic variance linked to breast cancer in young women, identifying a prognostic association with germline variation of ADAMTSL1.

Original languageEnglish (US)
Article number1632
JournalNature Communications
Volume8
Issue number1
DOIs
StatePublished - Dec 1 2017

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

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    Kadalayil, L., Khan, S., Nevanlinna, H., Fasching, P. A., Couch, F. J., Hopper, J. L., Liu, J., Maishman, T., Durcan, L., Gerty, S., Blomqvist, C., Rack, B., Janni, W., Collins, A., Eccles, D., & Tapper, W. (2017). Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women. Nature Communications, 8(1), [1632]. https://doi.org/10.1038/s41467-017-01775-y