Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women

Latha Kadalayil, Sofia Khan, Heli Nevanlinna, Peter A. Fasching, Fergus J Couch, John L. Hopper, Jianjun Liu, Tom Maishman, Lorraine Durcan, Sue Gerty, Carl Blomqvist, Brigitte Rack, Wolfgang Janni, Andrew Collins, Diana Eccles, William Tapper

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Genetic variance can influence breast cancer prognosis. Here, the authors conduct a meta-analysis to explore genetic variance linked to breast cancer in young women, identifying a prognostic association with germline variation of ADAMTSL1.

Original languageEnglish (US)
Article number1632
JournalNature Communications
Volume8
Issue number1
DOIs
StatePublished - Dec 1 2017

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Oncology
prognosis
breast
cancer
Breast Neoplasms
Meta-Analysis
Therapeutics

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

Cite this

Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women. / Kadalayil, Latha; Khan, Sofia; Nevanlinna, Heli; Fasching, Peter A.; Couch, Fergus J; Hopper, John L.; Liu, Jianjun; Maishman, Tom; Durcan, Lorraine; Gerty, Sue; Blomqvist, Carl; Rack, Brigitte; Janni, Wolfgang; Collins, Andrew; Eccles, Diana; Tapper, William.

In: Nature Communications, Vol. 8, No. 1, 1632, 01.12.2017.

Research output: Contribution to journalArticle

Kadalayil, L, Khan, S, Nevanlinna, H, Fasching, PA, Couch, FJ, Hopper, JL, Liu, J, Maishman, T, Durcan, L, Gerty, S, Blomqvist, C, Rack, B, Janni, W, Collins, A, Eccles, D & Tapper, W 2017, 'Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women', Nature Communications, vol. 8, no. 1, 1632. https://doi.org/10.1038/s41467-017-01775-y
Kadalayil, Latha ; Khan, Sofia ; Nevanlinna, Heli ; Fasching, Peter A. ; Couch, Fergus J ; Hopper, John L. ; Liu, Jianjun ; Maishman, Tom ; Durcan, Lorraine ; Gerty, Sue ; Blomqvist, Carl ; Rack, Brigitte ; Janni, Wolfgang ; Collins, Andrew ; Eccles, Diana ; Tapper, William. / Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women. In: Nature Communications. 2017 ; Vol. 8, No. 1.
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