Genetics of Heart Failure and Sudden Death

Matteo Vatta, Michael J. Ackerman

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and expressivity of the primary syndrome-associated mutation remains a daunting task.

Original languageEnglish (US)
Pages (from-to)507-514
Number of pages8
JournalHeart Failure Clinics
Volume6
Issue number4
DOIs
StatePublished - Oct 1 2010

Keywords

  • Coronary artery disease
  • Heart failure
  • Sudden death

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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