Genetics of Heart Failure and Sudden Death

Matteo Vatta; Michael J. Ackerman

doi:10.1016/j.hfc.2010.05.008

Genetics of Heart Failure and Sudden Death

Matteo Vatta, Michael J. Ackerman

Cardiovascular Medicine

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and expressivity of the primary syndrome-associated mutation remains a daunting task.

Original language	English (US)
Pages (from-to)	507-514
Number of pages	8
Journal	Heart Failure Clinics
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/j.hfc.2010.05.008
State	Published - Oct 2010

Keywords

Coronary artery disease
Heart failure
Sudden death

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.hfc.2010.05.008

Cite this

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title = "Genetics of Heart Failure and Sudden Death",

abstract = "Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and expressivity of the primary syndrome-associated mutation remains a daunting task.",

keywords = "Coronary artery disease, Heart failure, Sudden death",

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AU - Vatta, Matteo

AU - Ackerman, Michael J.

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AB - Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and expressivity of the primary syndrome-associated mutation remains a daunting task.

KW - Coronary artery disease

KW - Heart failure

KW - Sudden death

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Genetics of Heart Failure and Sudden Death

Abstract

Keywords

ASJC Scopus subject areas

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