Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines

Mary B. Daly; Robert Pilarski; Jennifer E. Axilbund; Michael Berry; Saundra S. Buys; Beth Crawford; Meagan Farmer; Susan Friedman; Judy E. Garber; Seema Khan; Catherine Klein; Wendy Kohlmann; Allison Kurian; Jennifer K. Litton; Lisa Madlensky; P. Kelly Marcom; Sofia D. Merajver; Kenneth Offit; Tuya Pal; Huma Rana; Gwen Reiser; Mark E. Robson; Kristen Mahoney Shannon; Elizabeth Swisher; Nicoleta C. Voian; Jeffrey N. Weitzel; Alison Whelan; Myra J. Wick; Georgia L. Wiesner; Mary Dwyer; Rashmi Kumar; Susan Darlow

doi:10.6004/jnccn.2016.0018

Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines

Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Michael Berry, Saundra S. Buys, Beth Crawford, Meagan Farmer, Susan Friedman, Judy E. Garber, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Huma RanaGwen Reiser, Mark E. Robson, Kristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Myra J. Wick, Georgia L. Wiesner, Mary Dwyer, Rashmi Kumar, Susan Darlow

Obstetrics/Gynecology

Research output: Contribution to journal › Review article › peer-review

110 Scopus citations

Abstract

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling and risk assessment and management for hereditary cancer syndromes. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer and are intended to assist with clinical and shared decision-making. These NCCN Guidelines Insights summarize major discussion points of the 2015 NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meeting. Major discussion topics this year included multigene testing, risk management recommendations for less common genetic mutations, and salpingectomy for ovarian cancer risk reduction. The panel also discussed revisions to genetic testing criteria that take into account ovarian cancer histology and personal history of pancreatic cancer.

Original language	English (US)
Pages (from-to)	153-162
Number of pages	10
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	14
Issue number	2
DOIs	https://doi.org/10.6004/jnccn.2016.0018
State	Published - Feb 1 2016

ASJC Scopus subject areas

Oncology

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Daly, M. B., Pilarski, R., Axilbund, J. E., Berry, M., Buys, S. S., Crawford, B., Farmer, M., Friedman, S., Garber, J. E., Khan, S., Klein, C., Kohlmann, W., Kurian, A., Litton, J. K., Madlensky, L., Marcom, P. K., Merajver, S. D., Offit, K., Pal, T., ... Darlow, S. (2016). Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 14(2), 153-162. https://doi.org/10.6004/jnccn.2016.0018

Daly, MB, Pilarski, R, Axilbund, JE, Berry, M, Buys, SS, Crawford, B, Farmer, M, Friedman, S, Garber, JE, Khan, S, Klein, C, Kohlmann, W, Kurian, A, Litton, JK, Madlensky, L, Marcom, PK, Merajver, SD, Offit, K, Pal, T, Rana, H, Reiser, G, Robson, ME, Shannon, KM, Swisher, E, Voian, NC, Weitzel, JN, Whelan, A, Wick, MJ, Wiesner, GL, Dwyer, M, Kumar, R & Darlow, S 2016, 'Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 14, no. 2, pp. 153-162. https://doi.org/10.6004/jnccn.2016.0018

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abstract = "The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling and risk assessment and management for hereditary cancer syndromes. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer and are intended to assist with clinical and shared decision-making. These NCCN Guidelines Insights summarize major discussion points of the 2015 NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meeting. Major discussion topics this year included multigene testing, risk management recommendations for less common genetic mutations, and salpingectomy for ovarian cancer risk reduction. The panel also discussed revisions to genetic testing criteria that take into account ovarian cancer histology and personal history of pancreatic cancer.",

author = "Daly, {Mary B.} and Robert Pilarski and Axilbund, {Jennifer E.} and Michael Berry and Buys, {Saundra S.} and Beth Crawford and Meagan Farmer and Susan Friedman and Garber, {Judy E.} and Seema Khan and Catherine Klein and Wendy Kohlmann and Allison Kurian and Litton, {Jennifer K.} and Lisa Madlensky and Marcom, {P. Kelly} and Merajver, {Sofia D.} and Kenneth Offit and Tuya Pal and Huma Rana and Gwen Reiser and Robson, {Mark E.} and Shannon, {Kristen Mahoney} and Elizabeth Swisher and Voian, {Nicoleta C.} and Weitzel, {Jeffrey N.} and Alison Whelan and Wick, {Myra J.} and Wiesner, {Georgia L.} and Mary Dwyer and Rashmi Kumar and Susan Darlow",

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AU - Reiser, Gwen

AU - Robson, Mark E.

AU - Shannon, Kristen Mahoney

AU - Swisher, Elizabeth

AU - Voian, Nicoleta C.

AU - Weitzel, Jeffrey N.

AU - Whelan, Alison

AU - Wick, Myra J.

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AU - Kumar, Rashmi

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Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines

Abstract

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