Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines

Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Michael Berry, Saundra S. Buys, Beth Crawford, Meagan Farmer, Susan Friedman, Judy E. Garber, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Huma RanaGwen Reiser, Mark E. Robson, Kristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Myra J Wick, Georgia L. Wiesner, Mary Dwyer, Rashmi Kumar, Susan Darlow

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling and risk assessment and management for hereditary cancer syndromes. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer and are intended to assist with clinical and shared decision-making. These NCCN Guidelines Insights summarize major discussion points of the 2015 NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meeting. Major discussion topics this year included multigene testing, risk management recommendations for less common genetic mutations, and salpingectomy for ovarian cancer risk reduction. The panel also discussed revisions to genetic testing criteria that take into account ovarian cancer histology and personal history of pancreatic cancer.

Original languageEnglish (US)
Pages (from-to)153-162
Number of pages10
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume14
Issue number2
StatePublished - Feb 1 2016

Fingerprint

Ovarian Neoplasms
Breast
Risk Management
Genetic Testing
Guidelines
Hereditary Neoplastic Syndromes
Salpingectomy
Genetic Counseling
Risk Reduction Behavior
Pancreatic Neoplasms
Decision Making
Histology
Breast Neoplasms
Mutation
Clinical Decision-Making

ASJC Scopus subject areas

  • Oncology

Cite this

Daly, M. B., Pilarski, R., Axilbund, J. E., Berry, M., Buys, S. S., Crawford, B., ... Darlow, S. (2016). Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 14(2), 153-162.

Genetic/familial high-risk assessment : Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines. / Daly, Mary B.; Pilarski, Robert; Axilbund, Jennifer E.; Berry, Michael; Buys, Saundra S.; Crawford, Beth; Farmer, Meagan; Friedman, Susan; Garber, Judy E.; Khan, Seema; Klein, Catherine; Kohlmann, Wendy; Kurian, Allison; Litton, Jennifer K.; Madlensky, Lisa; Marcom, P. Kelly; Merajver, Sofia D.; Offit, Kenneth; Pal, Tuya; Rana, Huma; Reiser, Gwen; Robson, Mark E.; Shannon, Kristen Mahoney; Swisher, Elizabeth; Voian, Nicoleta C.; Weitzel, Jeffrey N.; Whelan, Alison; Wick, Myra J; Wiesner, Georgia L.; Dwyer, Mary; Kumar, Rashmi; Darlow, Susan.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 14, No. 2, 01.02.2016, p. 153-162.

Research output: Contribution to journalArticle

Daly, MB, Pilarski, R, Axilbund, JE, Berry, M, Buys, SS, Crawford, B, Farmer, M, Friedman, S, Garber, JE, Khan, S, Klein, C, Kohlmann, W, Kurian, A, Litton, JK, Madlensky, L, Marcom, PK, Merajver, SD, Offit, K, Pal, T, Rana, H, Reiser, G, Robson, ME, Shannon, KM, Swisher, E, Voian, NC, Weitzel, JN, Whelan, A, Wick, MJ, Wiesner, GL, Dwyer, M, Kumar, R & Darlow, S 2016, 'Genetic/familial high-risk assessment: Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 14, no. 2, pp. 153-162.
Daly, Mary B. ; Pilarski, Robert ; Axilbund, Jennifer E. ; Berry, Michael ; Buys, Saundra S. ; Crawford, Beth ; Farmer, Meagan ; Friedman, Susan ; Garber, Judy E. ; Khan, Seema ; Klein, Catherine ; Kohlmann, Wendy ; Kurian, Allison ; Litton, Jennifer K. ; Madlensky, Lisa ; Marcom, P. Kelly ; Merajver, Sofia D. ; Offit, Kenneth ; Pal, Tuya ; Rana, Huma ; Reiser, Gwen ; Robson, Mark E. ; Shannon, Kristen Mahoney ; Swisher, Elizabeth ; Voian, Nicoleta C. ; Weitzel, Jeffrey N. ; Whelan, Alison ; Wick, Myra J ; Wiesner, Georgia L. ; Dwyer, Mary ; Kumar, Rashmi ; Darlow, Susan. / Genetic/familial high-risk assessment : Breast and ovarian, version 2.2015 Featured updates to the NCCN guidelines. In: JNCCN Journal of the National Comprehensive Cancer Network. 2016 ; Vol. 14, No. 2. pp. 153-162.
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