@article{f435401514e64667b2e616ce3be41577,
title = "Genetic variation of Omi/HtrA2 and Parkinson's disease",
abstract = "Variants in the Omi/HtrA2 gene have been nominated as a cause of Parkinson's disease. This sequencing study of Omi/HtrA2 in 95 probands with apparent autosomal dominant inheritance of Parkinson's disease did not identify any pathogenic mutations. In addition, there was no association between common variations in the Omi/HtrA2 gene and susceptibility to Parkinson's disease in any of our four patient-control series (n = 2373). Taken together our results do not support a role for Omi/HtrA2 variants in the pathogenesis of Parkinson's disease.",
keywords = "HtrA2, Mitochondria, Neurodegeneration, PARK13, PD",
author = "Ross, {Owen A.} and Soto, {Alexandra I.} and Carles Vilari{\~n}o-G{\"u}ell and Heckman, {Michael G.} and Diehl, {Nancy N.} and Hulihan, {Mary M.} and Aasly, {Jan O.} and Sigrid Sando and Gibson, {J. Mark} and Timothy Lynch and Anna Krygowska-Wajs and Grzegorz Opala and Maria Barcikowska and Krzysztof Czyzewski and Uitti, {Ryan J.} and Wszolek, {Zbigniew K.} and Farrer, {Matthew J.}",
note = "Funding Information: We would like to thank all those who have contributed to our research, particularly all the neurologists who have collaborated and provided clinical expertise and samples for our genetic studies. Mayo Clinic Florida has submitted samples from this study to the Coriell Repository at NIH. OAR, and the presented studies are funded by a Rapid Response Innovation Award from the Michael J. Fox Foundation, and in part by a Morris K. Udall Parkinson's Disease Research Center of Excellence (NINDS P50 #NS40256).",
year = "2008",
month = nov,
doi = "10.1016/j.parkreldis.2008.08.003",
language = "English (US)",
volume = "14",
pages = "539--543",
journal = "Parkinsonism and Related Disorders",
issn = "1353-8020",
publisher = "Elsevier BV",
number = "7",
}