Genetic stroke syndromes

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: This review describes the clinical and radiographic features, genetic determinants, and treatment options for the most well-characterized monogenic disorders associated with stroke.

RECENT FINDINGS: Stroke is a phenotype of many clinically important inherited disorders. Recognition of the clinical manifestations of genetic disorders associated with stroke is important for accurate diagnosis and prognosis. Genetic studies have led to the discovery of specific mutations associated with the clinical phenotypes of many inherited stroke syndromes.

SUMMARY: Several inherited causes of stroke have established and effective therapies, further underscoring the importance of timely diagnosis.

Original languageEnglish (US)
Pages (from-to)399-411
Number of pages13
JournalContinuum (Minneapolis, Minn.)
Volume20
Issue number2 Cerebrovascular Disease
DOIs
StatePublished - Apr 1 2014

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Stroke
Phenotype
Inborn Genetic Diseases
Mutation
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Genetic stroke syndromes. / Barrett, Kevin M; Meschia, James F.

In: Continuum (Minneapolis, Minn.), Vol. 20, No. 2 Cerebrovascular Disease, 01.04.2014, p. 399-411.

Research output: Contribution to journalArticle

Barrett, Kevin M ; Meschia, James F. / Genetic stroke syndromes. In: Continuum (Minneapolis, Minn.). 2014 ; Vol. 20, No. 2 Cerebrovascular Disease. pp. 399-411.
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