We have initiated studies to determine whether the antibody and T‐lymphocyte proliferative responses to lysozyme and its antigenic sites is genetically controlled in mice. Mice of the H‐2f, H‐2k and H‐2p were high responders, while haplotypes H‐2b, H‐2d, H‐2r and H‐2s were low responders. Studies with recombinants indicated that the immune response is controlled by two H‐2I region loci, one being in the I‐A subregion and the other may be in the I‐C subregions.
|Original language||English (US)|
|Number of pages||6|
|Journal||International Journal of Immunogenetics|
|State||Published - Dec 1979|
ASJC Scopus subject areas
- Molecular Biology