TY - JOUR
T1 - Genes with spiralian-specific protein motifs are expressed in spiralian ciliary bands
AU - Wu, Longjun
AU - Hiebert, Laurel S.
AU - Klann, Marleen
AU - Passamaneck, Yale
AU - Bastin, Benjamin R.
AU - Schneider, Stephan Q.
AU - Martindale, Mark Q.
AU - Seaver, Elaine C.
AU - Maslakova, Svetlana A.
AU - Lambert, J. David
N1 - Funding Information:
We would like to thank Paul Gonzalez from the Chris Lowe lab for sharing the unpublished transcriptome data of Phoronopsis harmeri. We would also like to thank Dr. Danielle de Jong for cloning the Capitella genes. This work was supported by two grants by the N.S.F. to J.D.L. (IOS-1146782 and IOS-1656558).
Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Spiralia is a large, ancient and diverse clade of animals, with a conserved early developmental program but diverse larval and adult morphologies. One trait shared by many spiralians is the presence of ciliary bands used for locomotion and feeding. To learn more about spiralian-specific traits we have examined the expression of 20 genes with protein motifs that are strongly conserved within the Spiralia, but not detectable outside of it. Here, we show that two of these are specifically expressed in the main ciliary band of the mollusc Tritia (also known as Ilyanassa). Their expression patterns in representative species from five more spiralian phyla—the annelids, nemerteans, phoronids, brachiopods and rotifers—show that at least one of these, lophotrochin, has a conserved and specific role in particular ciliated structures, most consistently in ciliary bands. These results highlight the potential importance of lineage-specific genes or protein motifs for understanding traits shared across ancient lineages.
AB - Spiralia is a large, ancient and diverse clade of animals, with a conserved early developmental program but diverse larval and adult morphologies. One trait shared by many spiralians is the presence of ciliary bands used for locomotion and feeding. To learn more about spiralian-specific traits we have examined the expression of 20 genes with protein motifs that are strongly conserved within the Spiralia, but not detectable outside of it. Here, we show that two of these are specifically expressed in the main ciliary band of the mollusc Tritia (also known as Ilyanassa). Their expression patterns in representative species from five more spiralian phyla—the annelids, nemerteans, phoronids, brachiopods and rotifers—show that at least one of these, lophotrochin, has a conserved and specific role in particular ciliated structures, most consistently in ciliary bands. These results highlight the potential importance of lineage-specific genes or protein motifs for understanding traits shared across ancient lineages.
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U2 - 10.1038/s41467-020-17780-7
DO - 10.1038/s41467-020-17780-7
M3 - Article
C2 - 32820176
AN - SCOPUS:85089662392
SN - 2041-1723
VL - 11
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 4171
ER -