Abstract
Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.
| Original language | English (US) |
|---|---|
| Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Editors | W.F. Walker, S.Y. Emelianov |
| Pages | 236-243 |
| Number of pages | 8 |
| Volume | 5750 |
| DOIs | |
| State | Published - 2005 |
| Event | Medical Imaging 2005 - Ultrasonic Imaging and Signal Processing - San Diego, CA, United States Duration: Feb 15 2005 → Feb 17 2005 |
Other
| Other | Medical Imaging 2005 - Ultrasonic Imaging and Signal Processing |
|---|---|
| Country | United States |
| City | San Diego, CA |
| Period | 2/15/05 → 2/17/05 |
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Keywords
- Artery
- Elastic modulus
- Pulse wave velocity
- Ring resonance
- Ultrasound
ASJC Scopus subject areas
- Engineering(all)
Cite this
Generation of ring resonant mode for measuring artery elastic modulus. / Zhang, Xiaoming; Greenleaf, James F.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. ed. / W.F. Walker; S.Y. Emelianov. Vol. 5750 2005. p. 236-243 27.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Generation of ring resonant mode for measuring artery elastic modulus
AU - Zhang, Xiaoming
AU - Greenleaf, James F
PY - 2005
Y1 - 2005
N2 - Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.
AB - Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.
KW - Artery
KW - Elastic modulus
KW - Pulse wave velocity
KW - Ring resonance
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=24644446464&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=24644446464&partnerID=8YFLogxK
U2 - 10.1117/12.592730
DO - 10.1117/12.592730
M3 - Conference contribution
VL - 5750
SP - 236
EP - 243
BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
A2 - Walker, W.F.
A2 - Emelianov, S.Y.
ER -