### Abstract

Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.

Original language | English (US) |
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Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |

Editors | W.F. Walker, S.Y. Emelianov |

Pages | 236-243 |

Number of pages | 8 |

Volume | 5750 |

DOIs | |

State | Published - 2005 |

Event | Medical Imaging 2005 - Ultrasonic Imaging and Signal Processing - San Diego, CA, United States Duration: Feb 15 2005 → Feb 17 2005 |

### Other

Other | Medical Imaging 2005 - Ultrasonic Imaging and Signal Processing |
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Country | United States |

City | San Diego, CA |

Period | 2/15/05 → 2/17/05 |

### Fingerprint

### Keywords

- Artery
- Elastic modulus
- Pulse wave velocity
- Ring resonance
- Ultrasound

### ASJC Scopus subject areas

- Engineering(all)

### Cite this

*Progress in Biomedical Optics and Imaging - Proceedings of SPIE*(Vol. 5750, pp. 236-243). [27] https://doi.org/10.1117/12.592730

**Generation of ring resonant mode for measuring artery elastic modulus.** / Zhang, Xiaoming; Greenleaf, James F.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Progress in Biomedical Optics and Imaging - Proceedings of SPIE.*vol. 5750, 27, pp. 236-243, Medical Imaging 2005 - Ultrasonic Imaging and Signal Processing, San Diego, CA, United States, 2/15/05. https://doi.org/10.1117/12.592730

}

TY - GEN

T1 - Generation of ring resonant mode for measuring artery elastic modulus

AU - Zhang, Xiaoming

AU - Greenleaf, James F

PY - 2005

Y1 - 2005

N2 - Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.

AB - Increased stiffness of the arteries has recently gained acceptance as an independent risk factor for cardiovascular and many other diseases. Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. From measured PWV, the diameter and thickness of the artery are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical or Doppler techniques. Three ring resonant modes are identified for estimation of the elastic modulus of the artery. Experiments on ring resonant frequencies were carried out on a porcine artery. The measurement results of the three resonant frequencies are, respectively, 356 Hz, 718 Hz, and 968 Hz. Estimation of the circumferential Young's modulus by the three measured frequencies are, respectively, 135 kPa, 137 kPa, and 125 kPa. The estimated modulus is very consistent with the three resonant frequency measurements. The values of these three estimations are well within the range of arterial elastic modulus from published papers. With this method, the estimation of the Young's modulus of the artery only requires the diameter of the artery, but doesn't need the thickness of the artery which is difficult to measure with accuracy and precision.

KW - Artery

KW - Elastic modulus

KW - Pulse wave velocity

KW - Ring resonance

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=24644446464&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=24644446464&partnerID=8YFLogxK

U2 - 10.1117/12.592730

DO - 10.1117/12.592730

M3 - Conference contribution

AN - SCOPUS:24644446464

VL - 5750

SP - 236

EP - 243

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

A2 - Walker, W.F.

A2 - Emelianov, S.Y.

ER -