General anesthesia and respiratory mechanics

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The study of respiratory mechanics concerns the motion of structures that control the movement of air into and out of the lungs. One set of structures controls intrathoracic pressure, which drives gas flow; these structures comprise the chest wall. Another system maintains the patency of the extrathoracic airway proximal to the glottis; the components of this system comprise the upper airway. This chapter will describe the functional consequences of anesthetic-induced alterations in the activation of skeletal muscles that control the chest wall and upper airway (often referred to as respiratory muscles). Anesthetics also have important effects on smooth muscle lining the airways, which also regulates gas flow within the lungs. This topic is reviewed elsewhere [1] and is beyond the scope of this chapter. Historically, simple observation of external respiratory system motion provided a powerful tool to guide the proper administration of anesthesia [2]. More recently, alterations in the control of respiratory muscles that lead to changes in respiratory mechanics have been invoked to explain much of the impairment of gas exchange observed during and after clinical anesthesia. Thus, anesthetic-induced changes in respiratory muscle activation and respiratory mechanics can have profound clinical consequences.

Original languageEnglish (US)
Title of host publicationPharmacology and Pathophysiology of the Control of Breathing
PublisherCRC Press
Pages687-735
Number of pages49
ISBN (Electronic)9780849359538
ISBN (Print)9780824758905
StatePublished - Jan 1 2005

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Respiratory Mechanics
Respiratory Muscles
General Anesthesia
Anesthetics
Gases
Thoracic Wall
Anesthesia
Air Movements
Glottis
Lung
Respiratory System
Smooth Muscle
Skeletal Muscle
Observation
Pressure

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Warner, D. O. (2005). General anesthesia and respiratory mechanics. In Pharmacology and Pathophysiology of the Control of Breathing (pp. 687-735). CRC Press.

General anesthesia and respiratory mechanics. / Warner, David Oman.

Pharmacology and Pathophysiology of the Control of Breathing. CRC Press, 2005. p. 687-735.

Research output: Chapter in Book/Report/Conference proceedingChapter

Warner, DO 2005, General anesthesia and respiratory mechanics. in Pharmacology and Pathophysiology of the Control of Breathing. CRC Press, pp. 687-735.
Warner DO. General anesthesia and respiratory mechanics. In Pharmacology and Pathophysiology of the Control of Breathing. CRC Press. 2005. p. 687-735
Warner, David Oman. / General anesthesia and respiratory mechanics. Pharmacology and Pathophysiology of the Control of Breathing. CRC Press, 2005. pp. 687-735
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