Gemcitabine-Induced Radiation Recall Myositis: Case Report and Review of the Literature

Adarsh Ravishankar, Sean S. Park, Kenneth R. Olivier, Kimberly S. Corbin

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Gemcitabine-induced radiation recall (GIRR) is a phenomenon wherein the administration of gemcitabine induces an inflammatory reaction within an area of prior radiation. We present the case of a 39-year-old female patient with metastatic breast cancer who experienced GIRR myositis 3 months following postoperative radiotherapy, with additional potential paraspinal myositis following ablative radiotherapy to the thoracic spine. A review of previously published cases of GIRR myositis was performed. The case and literature review describe the clinical course and presentation of GIRR, and highlight the importance of including radiation recall as part of a differential diagnosis when a patient undergoing chemotherapy experiences an inflammatory reaction at a prior site of radiation.

Original languageEnglish (US)
Pages (from-to)168-178
Number of pages11
JournalCase Reports in Oncology
Volume11
Issue number1
DOIs
StatePublished - Jan 19 2018

Keywords

  • Bone metastasis
  • Breast cancer
  • Gemcitabine
  • Radiation

ASJC Scopus subject areas

  • Oncology

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