Abstract
Gemcitabine-induced radiation recall (GIRR) is a phenomenon wherein the administration of gemcitabine induces an inflammatory reaction within an area of prior radiation. We present the case of a 39-year-old female patient with metastatic breast cancer who experienced GIRR myositis 3 months following postoperative radiotherapy, with additional potential paraspinal myositis following ablative radiotherapy to the thoracic spine. A review of previously published cases of GIRR myositis was performed. The case and literature review describe the clinical course and presentation of GIRR, and highlight the importance of including radiation recall as part of a differential diagnosis when a patient undergoing chemotherapy experiences an inflammatory reaction at a prior site of radiation.
Original language | English (US) |
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Pages (from-to) | 168-178 |
Number of pages | 11 |
Journal | Case Reports in Oncology |
Volume | 11 |
Issue number | 1 |
DOIs | |
State | Published - Jan 19 2018 |
Keywords
- Bone metastasis
- Breast cancer
- Gemcitabine
- Radiation
ASJC Scopus subject areas
- Oncology