TY - JOUR
T1 - Gastroschisis
T2 - a systematic review of diagnosis, prognosis and treatment
AU - Ferreira, Rui Gilberto
AU - Mendonça, Carolina Rodrigues
AU - Gonçalves Ramos, Lelia Luanne
AU - de Abreu Tacon, Fernanda Sardinha
AU - Naves do Amaral, Waldemar
AU - Ruano, Rodrigo
N1 - Funding Information:
Universidade Federal de Goiás for partial supporting. Source(s) of financial support for the research: Own resources. This research received no external funding.
Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - Objectives: The present systematic review aims to investigate the diagnosis, prognosis, delivery assistance, pregnancy results and postnatal management in gastroschisis. Study design: The following data sources were evaluated: The CINAHL, Embase and MEDLINE/PubMed databases were searched, observational and intervention studies published over the past 20 years. The quality of the studies was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE). Results: A total of 3770 infants diagnosed with gastroschisis were included (44 studies); 1534 fetuses were classified as simple gastroschisis and 288 as complex gastroschisis. Intrauterine fetal demise occurred in 0.47% and elective termination occurred in 0.13%. Preterm delivery occurred in 23.23% and intrauterine growth restriction in 4.43%. Cesarean section delivery was performed in 54.6%. Neonatal survival was 91.29%. The main neonatal complications were: sepsis (11.78%), necrotizing enterocolitis (2.33%), short bowel syndrome (1.37%), bowel obstruction (0.79%), and volvulus (0.23%). Immediate surgical repair was performed in 80.1% with primary closure in 69%. The average to oral feeding was 33 (range: 11–124.5) days. Average hospital duration was 38 days and 89 days in neonates with simple and complex grastroschisis, respectively. Conclusions: The present systematic review provides scientific data for counseling families with fetal gastroschisis.
AB - Objectives: The present systematic review aims to investigate the diagnosis, prognosis, delivery assistance, pregnancy results and postnatal management in gastroschisis. Study design: The following data sources were evaluated: The CINAHL, Embase and MEDLINE/PubMed databases were searched, observational and intervention studies published over the past 20 years. The quality of the studies was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE). Results: A total of 3770 infants diagnosed with gastroschisis were included (44 studies); 1534 fetuses were classified as simple gastroschisis and 288 as complex gastroschisis. Intrauterine fetal demise occurred in 0.47% and elective termination occurred in 0.13%. Preterm delivery occurred in 23.23% and intrauterine growth restriction in 4.43%. Cesarean section delivery was performed in 54.6%. Neonatal survival was 91.29%. The main neonatal complications were: sepsis (11.78%), necrotizing enterocolitis (2.33%), short bowel syndrome (1.37%), bowel obstruction (0.79%), and volvulus (0.23%). Immediate surgical repair was performed in 80.1% with primary closure in 69%. The average to oral feeding was 33 (range: 11–124.5) days. Average hospital duration was 38 days and 89 days in neonates with simple and complex grastroschisis, respectively. Conclusions: The present systematic review provides scientific data for counseling families with fetal gastroschisis.
KW - Gastroschisis
KW - diagnostic imaging
KW - postnatal care
KW - prenatal diagnosis
KW - prognosis
KW - ultrasonography
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U2 - 10.1080/14767058.2021.1909563
DO - 10.1080/14767058.2021.1909563
M3 - Review article
C2 - 33899664
AN - SCOPUS:85105090954
SN - 1476-7058
VL - 35
SP - 6199
EP - 6212
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
IS - 25
ER -