Gastrointestinal sensation. Mechanisms and relation to functional gastrointestinal disorders

M. Camilleri; S. B. Saslow; A. E. Bharucha

doi:10.1016/S0889-8553(05)70374-5

Gastrointestinal sensation. Mechanisms and relation to functional gastrointestinal disorders

M. Camilleri, S. B. Saslow, A. E. Bharucha

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

This article reviews the basic anatomy and physiology of visceral afferent function and its application to a clearer understanding of visceral pain and symptoms in patients with functional gastrointestinal disorders. Recent investigations have focused on the potential role of visceral tone, different afferent (A delta and C) fibers, dorsal column neurons, and supraspinal modulation in the elicitation of visceral perception of noxious and nonnoxious stimuli arising in the gut. Greater understanding of these pathomechanisms and their pharmacologic manipulation offers an opportunity for future therapeutic strategies for these disorders.

Original language	English (US)
Pages (from-to)	247-258
Number of pages	12
Journal	Gastroenterology Clinics of North America
Volume	25
Issue number	1
DOIs	https://doi.org/10.1016/S0889-8553(05)70374-5
State	Published - 1996

ASJC Scopus subject areas

Gastroenterology

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10.1016/S0889-8553(05)70374-5

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Gastrointestinal sensation. Mechanisms and relation to functional gastrointestinal disorders

Abstract

ASJC Scopus subject areas

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