Gastric polyps and polyposis syndromes

Dora Lam-Himlin, Christina A. Arnold, Giovanni De Petris

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Gastric polyps show significant morphologic overlap, and some polyps defy classification altogether. Nevertheless, gastric polyps, particularly when profuse, should prompt further clinical and endoscopic investigation, as it may lead to the diagnosis of a polyposis syndrome. This review summarizes the common gastric polyps that are found in familial and non-inherited polyposis syndromes of the gastrointestinal tract. Examples of the gastric polyps are illustrated, and a discussion of polyp morphology and distribution is paired with a discussion of relevant clinical features and diagnostic criteria of polyposis syndromes. This information provides pathologists guidance for further patient workup, genetic testing, and cancer surveillance.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalDiagnostic Histopathology
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2014

Keywords

  • Cowden syndrome
  • Cronkhite-Cananda syndrome
  • Familial adenomatous polyposis
  • Fundic gland polyposis
  • Hamartomatous intestinal polyposis
  • Juvenile polyposis syndrome
  • Peutz-Jeghers syndrome

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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  • Cite this

    Lam-Himlin, D., Arnold, C. A., & De Petris, G. (2014). Gastric polyps and polyposis syndromes. Diagnostic Histopathology, 20(1), 1-11. https://doi.org/10.1016/j.mpdhp.2013.12.002