Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers

A. A. Hayes, B. Mullan, F. T. Lovegrove, A. H. Rose, A. W. Musk, B. W. Robinson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Gallium lung scanning is widely used to evaluate pulmonary inflammation in patients with interstitial lung disease but has not previously been reported in crocidolite-exposed workers. In order to characterize the pulmonary inflammation caused by crocidolite inhalation, GLS and BAL findings were related to chest x-ray film changes graded according to the ILO classification of roentgenograms of pneumoconioses. In individuals with roentgenographic evidence of asbestosis (CXR ≥ 1/0, n = 15), 13 had a positive GLS and 13 had an abnormal BAL. In asbestos-exposed individuals with equivocal chest x-ray film changes (CXR 0/1, n = 12), six had a positive GLS and six had BAL changes (both GLS and BAL abnormal in three). In individuals with a normal chest x-ray film (CXR 0/0 n = 8), two had a positive GLS and two BAL changes (both abnormal in 1). These data demonstrate that most subjects with crocidolite-induced asbestosis have an abnormal GLS and BAL. In addition, many individuals with asbestos exposure and equivocal or no chest x-ray film changes have an abnormal GLS and/or BAL, suggesting the presence of active subclinical pulmonary inflammation in these individuals.

Original languageEnglish (US)
Pages (from-to)22-26
Number of pages5
JournalChest
Volume96
Issue number1
StatePublished - 1989
Externally publishedYes

Fingerprint

Crocidolite Asbestos
Dimercaprol
Gallium
Bronchoalveolar Lavage
Motion Pictures
Thorax
X-Rays
Asbestosis
Pneumonia
Asbestos
Pneumoconiosis
Interstitial Lung Diseases
Inhalation
Lung

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Hayes, A. A., Mullan, B., Lovegrove, F. T., Rose, A. H., Musk, A. W., & Robinson, B. W. (1989). Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers. Chest, 96(1), 22-26.

Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers. / Hayes, A. A.; Mullan, B.; Lovegrove, F. T.; Rose, A. H.; Musk, A. W.; Robinson, B. W.

In: Chest, Vol. 96, No. 1, 1989, p. 22-26.

Research output: Contribution to journalArticle

Hayes, AA, Mullan, B, Lovegrove, FT, Rose, AH, Musk, AW & Robinson, BW 1989, 'Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers', Chest, vol. 96, no. 1, pp. 22-26.
Hayes AA, Mullan B, Lovegrove FT, Rose AH, Musk AW, Robinson BW. Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers. Chest. 1989;96(1):22-26.
Hayes, A. A. ; Mullan, B. ; Lovegrove, F. T. ; Rose, A. H. ; Musk, A. W. ; Robinson, B. W. / Gallium lung scanning and bronchoalveolar lavage in crocidolite-exposed workers. In: Chest. 1989 ; Vol. 96, No. 1. pp. 22-26.
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