Gadolinium enhancement of the lumbar roots in a case of ALS

Nathan P. Young; Ruple S. Laughlin; Eric J. Sorenson

doi:10.3109/17482960802642161

Gadolinium enhancement of the lumbar roots in a case of ALS

Nathan P. Young, Ruple S. Laughlin, Eric J. Sorenson

Neurology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.

Original language	English (US)
Pages (from-to)	207-209
Number of pages	3
Journal	Amyotrophic Lateral Sclerosis
Volume	11
Issue number	1-2
DOIs	https://doi.org/10.3109/17482960802642161
State	Published - 2010

Keywords

Amyotrophic lateral sclerosis
Magnetic resonance imaging
Motor neuron disease

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.3109/17482960802642161

Cite this

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abstract = "We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.",

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AU - Young, Nathan P.

AU - Laughlin, Ruple S.

AU - Sorenson, Eric J.

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N2 - We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.

AB - We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.

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KW - Magnetic resonance imaging

KW - Motor neuron disease

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Gadolinium enhancement of the lumbar roots in a case of ALS

Abstract

Keywords

ASJC Scopus subject areas

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