Gadolinium Enhanced Magnetic Resonance Urography for Upper Urinary Tract Malignancy

Naoki Takahashi, James Glockner, Robert P. Hartman, Bernard Francis King, Bradley C. Leibovich, David W. Stanley, Patrick D. Fitz-Gibbon, Akira Kawashima

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Purpose: We retrospectively evaluated the accuracy of gadolinium enhanced magnetic resonance urography to detect upper urinary tract tumors. Materials and Methods: A total of 91 magnetic resonance urography studies for suspected upper tract malignancy were done in 70 males and 18 females with a mean age of 71.7 years. Breath hold coronal T2-weighted single shot fast spin-echo and breath-hold coronal 3-dimensional T1-weighted spoiled gradient-recalled echo images with fat suppression were obtained during the nephrographic and excretory phases after intravenous injection of gadolinium based contrast material. Two radiologists independently reviewed magnetic resonance images for a tumor by 4 regions (right/left and renal collecting system/ureter). Sensitivity, specificity and accuracy were calculated. Results: A total of 35 urinary tract regions in 18 males and 7 females with a mean age of 70.4 years were confirmed to have an upper tract malignant tumor and 219 urinary tract regions were confirmed to be tumor-free. Sensitivity, specificity and accuracy to detect upper urinary tract malignancy were 74.3%, 96.8% and 93.7% for reviewer 1, and 62.9%, 96.3% and 91.7% for reviewer 2, respectively. When patients with a ureteral stent or nephrostomy tube were excluded from analysis, sensitivity, specificity and accuracy were 86.2%, 99.5% and 97.7% for reviewer 1, and 72.4%, 97.9% and 94.6% for reviewer 2, respectively. Conclusions: Gadolinium enhanced magnetic resonance urography is accurate to detect upper urinary tract malignant tumors.

Original languageEnglish (US)
Pages (from-to)1330-1336
Number of pages7
JournalJournal of Urology
Volume183
Issue number4
DOIs
StatePublished - Apr 2010

Fingerprint

Urography
Gadolinium
Urinary Tract
Magnetic Resonance Spectroscopy
Neoplasms
Sensitivity and Specificity
Ureter
Intravenous Injections
Contrast Media
Stents
Fats
Kidney

Keywords

  • carcinoma
  • contrast media
  • diagnosis
  • magnetic resonance imaging
  • urinary tract

ASJC Scopus subject areas

  • Urology

Cite this

Gadolinium Enhanced Magnetic Resonance Urography for Upper Urinary Tract Malignancy. / Takahashi, Naoki; Glockner, James; Hartman, Robert P.; King, Bernard Francis; Leibovich, Bradley C.; Stanley, David W.; Fitz-Gibbon, Patrick D.; Kawashima, Akira.

In: Journal of Urology, Vol. 183, No. 4, 04.2010, p. 1330-1336.

Research output: Contribution to journalArticle

Takahashi, Naoki ; Glockner, James ; Hartman, Robert P. ; King, Bernard Francis ; Leibovich, Bradley C. ; Stanley, David W. ; Fitz-Gibbon, Patrick D. ; Kawashima, Akira. / Gadolinium Enhanced Magnetic Resonance Urography for Upper Urinary Tract Malignancy. In: Journal of Urology. 2010 ; Vol. 183, No. 4. pp. 1330-1336.
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