Gadolinium-DTPA - Enhanced magnetic resonance imaging in intractable partial epilepsy

Gregory D Cascino, K. A. Hirschorn, Clifford R Jr. Jack, F. W. Sharbrough

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Abstract

We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.

Original languageEnglish (US)
Pages (from-to)1115-1118
Number of pages4
JournalNeurology
Volume39
Issue number8
StatePublished - 1989

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Gadolinium DTPA
Partial Epilepsy
Magnetic Resonance Imaging
Epilepsy
Drug Resistant Epilepsy
Therapeutics

ASJC Scopus subject areas

  • Neuroscience(all)

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Gadolinium-DTPA - Enhanced magnetic resonance imaging in intractable partial epilepsy. / Cascino, Gregory D; Hirschorn, K. A.; Jack, Clifford R Jr.; Sharbrough, F. W.

In: Neurology, Vol. 39, No. 8, 1989, p. 1115-1118.

Research output: Contribution to journalArticle

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