TY - JOUR
T1 - Gadolinium-DTPA- enhanced magnetic resonance imaging in intractable partial epilepsy
AU - Cascino, Gregory D.
AU - Hirschorn, Kathryn A.
AU - Jack, Clifford R.
AU - Sharbrough, Frank W.
PY - 1989/8
Y1 - 1989/8
N2 - We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.
AB - We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.
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U2 - 10.1212/wnl.39.8.1115
DO - 10.1212/wnl.39.8.1115
M3 - Article
C2 - 2503770
AN - SCOPUS:0024450779
SN - 0028-3878
VL - 39
SP - 1115
EP - 1118
JO - Neurology
JF - Neurology
IS - 8
ER -