TY - JOUR
T1 - Further guaianolides from Amphoricarpos neumayeri ssp. murbeckii from Montenegro
AU - Djordjević, Iris
AU - Jadranin, Milka
AU - Vajs, Vlatka
AU - Menković, Nebojša
AU - Tešević, Vele
AU - Macura, Slobodan
AU - Milosavljević, Slobodan
N1 - Funding Information:
The authors from Serbia acknowledge their gratitude to the Ministry of Science and Ecology of Serbia (Project 142053) for financial support. We also wish to express our gratitude to Daniel Vincek, Botanic Garden, Dulovine, Kolasˇin (Montenegro) and Milutin Prasˇcˇević, Alpinetum of Prokletije, Plav (Montenegro) for the immense help in collecting the plant material.
PY - 2006/11
Y1 - 2006/11
N2 - The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1αH,4βH,5αH,7αH) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4α-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10α(14)-position. Instead of the Δ11(13)-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11α,13-diol (8-10) or 11α-OH,13-chloro (11) moieties respectively.
AB - The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1αH,4βH,5αH,7αH) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4α-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10α(14)-position. Instead of the Δ11(13)-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11α,13-diol (8-10) or 11α-OH,13-chloro (11) moieties respectively.
KW - Amphoricarpos neumayeri ssp. murbeckii
KW - Guaianolides
KW - Sesquiterpene lactones
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U2 - 10.1515/znb-2006-1119
DO - 10.1515/znb-2006-1119
M3 - Article
AN - SCOPUS:33845648057
SN - 0932-0776
VL - 61
SP - 1437
EP - 1442
JO - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
JF - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
IS - 11
ER -