The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1αH,4βH,5αH,7αH) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4α-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10α(14)-position. Instead of the Δ11(13)-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11α,13-diol (8-10) or 11α-OH,13-chloro (11) moieties respectively.
|Original language||English (US)|
|Number of pages||6|
|Journal||Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences|
|State||Published - Nov 2006|
- Amphoricarpos neumayeri ssp. murbeckii
- Sesquiterpene lactones
ASJC Scopus subject areas