Further guaianolides from Amphoricarpos neumayeri ssp. murbeckii from Montenegro

Iris Djordjević, Milka Jadranin, Vlatka Vajs, Nebojša Menković, Vele Tešević, Slobodan Macura, Slobodan Milosavljević

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1αH,4βH,5αH,7αH) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4α-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10α(14)-position. Instead of the Δ11(13)-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11α,13-diol (8-10) or 11α-OH,13-chloro (11) moieties respectively.

Original languageEnglish (US)
Pages (from-to)1437-1442
Number of pages6
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume61
Issue number11
DOIs
StatePublished - Nov 2006

Keywords

  • Amphoricarpos neumayeri ssp. murbeckii
  • Guaianolides
  • Sesquiterpene lactones

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Further guaianolides from Amphoricarpos neumayeri ssp. murbeckii from Montenegro'. Together they form a unique fingerprint.

  • Cite this