Further guaianolides from Amphoricarpos neumayeri ssp. murbeckii from Montenegro

Iris Djordjević, Milka Jadranin, Vlatka Vajs, Nebojša Menković, Vele Tešević, Slobodan Macura, Slobodan Milosavljević

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1αH,4βH,5αH,7αH) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4α-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10α(14)-position. Instead of the Δ11(13)-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11α,13-diol (8-10) or 11α-OH,13-chloro (11) moieties respectively.

Original languageEnglish (US)
Pages (from-to)1437-1442
Number of pages6
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume61
Issue number11
DOIs
StatePublished - Nov 2006

Keywords

  • Amphoricarpos neumayeri ssp. murbeckii
  • Guaianolides
  • Sesquiterpene lactones

ASJC Scopus subject areas

  • Chemistry(all)

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