Abstract
Repeated examination of the aerial parts of Hypericum perforatum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3- pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 439-444 |
| Number of pages | 6 |
| Journal | Fitoterapia |
| Volume | 74 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jul 2003 |
Fingerprint
Keywords
- Antimicrobial activity
- Deoxyfurohyperforin A
- Hypericum perforatum
ASJC Scopus subject areas
- Pharmacology
Cite this
Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort). / Vajs, V.; Vugdelija, S.; Trifunović, S.; Karadžić, I.; Juranić, N.; Macura, Slobodan I; Milosavljević, S.
In: Fitoterapia, Vol. 74, No. 5, 07.2003, p. 439-444.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort)
AU - Vajs, V.
AU - Vugdelija, S.
AU - Trifunović, S.
AU - Karadžić, I.
AU - Juranić, N.
AU - Macura, Slobodan I
AU - Milosavljević, S.
PY - 2003/7
Y1 - 2003/7
N2 - Repeated examination of the aerial parts of Hypericum perforatum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3- pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli.
AB - Repeated examination of the aerial parts of Hypericum perforatum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3- pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli.
KW - Antimicrobial activity
KW - Deoxyfurohyperforin A
KW - Hypericum perforatum
UR - http://www.scopus.com/inward/record.url?scp=0038691833&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038691833&partnerID=8YFLogxK
U2 - 10.1016/S0367-326X(03)00114-X
DO - 10.1016/S0367-326X(03)00114-X
M3 - Article
C2 - 12837358
AN - SCOPUS:0038691833
VL - 74
SP - 439
EP - 444
JO - Fitoterapia
JF - Fitoterapia
SN - 0367-326X
IS - 5
ER -