Fungal Infections After Lung Transplantation

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Infection remains a significant source of morbidity and mortality after lung transplant, including fungal infection. Various antifungal prophylactic agents are administered for a variable duration after transplant with the goal of preventing invasive fungal infections. Alternatively, some programs target the use of antifungal agents only in those colonized with Aspergillus spp. Despite prophylaxis or preemptive therapy, a significant number of invasive fungal infections occur after lung transplant. Risk factors for fungal infections include single lung transplant, pretransplant Aspergillus colonization, environmental risks, structural lung disease such as cystic fibrosis, augmented immunosuppression, sinus disease, and use of indwelling airway stents.

Original languageEnglish (US)
Pages (from-to)511-520
Number of pages10
JournalClinics in Chest Medicine
Volume38
Issue number3
DOIs
StatePublished - Sep 2017

Keywords

  • Fungal infection
  • Fungal prophylaxis
  • Lung transplantation
  • Solid organ transplantation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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