Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass

Shounak Majumder, Joanna Grabska, Guru Trikudanathan, Pamela Kowalczyk, Elena Stoica-Mustafa, Constantin A. Dasanu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Pheochromocytomas rarely have 'composite' forms in which they demonstrate histologic features of a typical paraganglioma in combination with those of a neural component. Extra-adrenal 'composite' pheochromocytomas are distinctly uncommon.We describe herein a unique case of a 34-year-old female patient with type 1 neurofibromatosis who presented with abdominal pain and paroxysmal hypertension. Imaging revealed a pancreatic mass with biliary and pancreatic ductal dilatation and a hormonal assay led to the diagnosis of functional pheochromocytoma. She underwent surgical resection and histopathology revealed a composite paragangliomaeganglioneuroma. Clinical, biochemical and radiological aspects of this rare tumor and its association with neurofibromatosis and other hereditary cancer syndromes are discussed.

Original languageEnglish (US)
Pages (from-to)211-214
Number of pages4
JournalPancreatology
Volume12
Issue number3
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Fingerprint

Pheochromocytoma
Hereditary Neoplastic Syndromes
Paraganglioma
Neurofibromatoses
Neurofibromatosis 1
Abdominal Pain
Dilatation
Hypertension
Neoplasms

Keywords

  • Ganglioneuroma
  • Neuroendocrine tumor
  • Pancreas
  • Paraganglioma

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Majumder, S., Grabska, J., Trikudanathan, G., Kowalczyk, P., Stoica-Mustafa, E., & Dasanu, C. A. (2012). Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass. Pancreatology, 12(3), 211-214. https://doi.org/10.1016/j.pan.2012.02.001

Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass. / Majumder, Shounak; Grabska, Joanna; Trikudanathan, Guru; Kowalczyk, Pamela; Stoica-Mustafa, Elena; Dasanu, Constantin A.

In: Pancreatology, Vol. 12, No. 3, 01.01.2012, p. 211-214.

Research output: Contribution to journalArticle

Majumder, S, Grabska, J, Trikudanathan, G, Kowalczyk, P, Stoica-Mustafa, E & Dasanu, CA 2012, 'Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass', Pancreatology, vol. 12, no. 3, pp. 211-214. https://doi.org/10.1016/j.pan.2012.02.001
Majumder S, Grabska J, Trikudanathan G, Kowalczyk P, Stoica-Mustafa E, Dasanu CA. Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass. Pancreatology. 2012 Jan 1;12(3):211-214. https://doi.org/10.1016/j.pan.2012.02.001
Majumder, Shounak ; Grabska, Joanna ; Trikudanathan, Guru ; Kowalczyk, Pamela ; Stoica-Mustafa, Elena ; Dasanu, Constantin A. / Functional 'composite' pheochromocytomaeganglioneuroma presenting as a pancreatic mass. In: Pancreatology. 2012 ; Vol. 12, No. 3. pp. 211-214.
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