Fulminant case of hereditary neuropathy with liability to pressure palsy

Brian A. Crum, Eric James Sorenson, Gregorio A. Abad, P. James B Dyck

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Hereditary neuropathy with liability to pressure palsy (HNPP) is typified as isolated nerve palsies caused by trivial compression or trauma. It rarely presents in two extremities and even more infrequently affects all four limbs simultaneously. We present a patient who concurrently experienced right shoulder, left hand, and bilateral foot weakness mimicking several multifocal conditions. Electromyography suggested HNPP and subsequent nerve biopsy and genetic testing were confirmatory. The case demonstrates that HNPP can present in a fulminant manner and should be included in the differential diagnosis of acute multiple mononeuropathies. The possible causes for such a rapid clinical course in our patient are discussed. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish (US)
Pages (from-to)979-983
Number of pages5
JournalMuscle and Nerve
Volume23
Issue number6
DOIs
StatePublished - 2000

Fingerprint

Extremities
Mononeuropathies
Genetic Testing
Electromyography
Paralysis
Foot
Differential Diagnosis
Hand
Biopsy
Wounds and Injuries
Tomaculous neuropathy

Keywords

  • Hereditary neuropathy
  • Hereditary neuropathy with liability to pressure palsies
  • Peripheral neuropathy
  • Polyradiculoneuropathy
  • Tomaculae

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Fulminant case of hereditary neuropathy with liability to pressure palsy. / Crum, Brian A.; Sorenson, Eric James; Abad, Gregorio A.; Dyck, P. James B.

In: Muscle and Nerve, Vol. 23, No. 6, 2000, p. 979-983.

Research output: Contribution to journalArticle

@article{42675d0a175c489e8d1af975ef674044,
title = "Fulminant case of hereditary neuropathy with liability to pressure palsy",
abstract = "Hereditary neuropathy with liability to pressure palsy (HNPP) is typified as isolated nerve palsies caused by trivial compression or trauma. It rarely presents in two extremities and even more infrequently affects all four limbs simultaneously. We present a patient who concurrently experienced right shoulder, left hand, and bilateral foot weakness mimicking several multifocal conditions. Electromyography suggested HNPP and subsequent nerve biopsy and genetic testing were confirmatory. The case demonstrates that HNPP can present in a fulminant manner and should be included in the differential diagnosis of acute multiple mononeuropathies. The possible causes for such a rapid clinical course in our patient are discussed. (C) 2000 John Wiley and Sons, Inc.",
keywords = "Hereditary neuropathy, Hereditary neuropathy with liability to pressure palsies, Peripheral neuropathy, Polyradiculoneuropathy, Tomaculae",
author = "Crum, {Brian A.} and Sorenson, {Eric James} and Abad, {Gregorio A.} and Dyck, {P. James B}",
year = "2000",
doi = "10.1002/(SICI)1097-4598(200006)23:6<979::AID-MUS23>3.0.CO;2-0",
language = "English (US)",
volume = "23",
pages = "979--983",
journal = "Muscle and Nerve",
issn = "0148-639X",
publisher = "John Wiley and Sons Inc.",
number = "6",

}

TY - JOUR

T1 - Fulminant case of hereditary neuropathy with liability to pressure palsy

AU - Crum, Brian A.

AU - Sorenson, Eric James

AU - Abad, Gregorio A.

AU - Dyck, P. James B

PY - 2000

Y1 - 2000

N2 - Hereditary neuropathy with liability to pressure palsy (HNPP) is typified as isolated nerve palsies caused by trivial compression or trauma. It rarely presents in two extremities and even more infrequently affects all four limbs simultaneously. We present a patient who concurrently experienced right shoulder, left hand, and bilateral foot weakness mimicking several multifocal conditions. Electromyography suggested HNPP and subsequent nerve biopsy and genetic testing were confirmatory. The case demonstrates that HNPP can present in a fulminant manner and should be included in the differential diagnosis of acute multiple mononeuropathies. The possible causes for such a rapid clinical course in our patient are discussed. (C) 2000 John Wiley and Sons, Inc.

AB - Hereditary neuropathy with liability to pressure palsy (HNPP) is typified as isolated nerve palsies caused by trivial compression or trauma. It rarely presents in two extremities and even more infrequently affects all four limbs simultaneously. We present a patient who concurrently experienced right shoulder, left hand, and bilateral foot weakness mimicking several multifocal conditions. Electromyography suggested HNPP and subsequent nerve biopsy and genetic testing were confirmatory. The case demonstrates that HNPP can present in a fulminant manner and should be included in the differential diagnosis of acute multiple mononeuropathies. The possible causes for such a rapid clinical course in our patient are discussed. (C) 2000 John Wiley and Sons, Inc.

KW - Hereditary neuropathy

KW - Hereditary neuropathy with liability to pressure palsies

KW - Peripheral neuropathy

KW - Polyradiculoneuropathy

KW - Tomaculae

UR - http://www.scopus.com/inward/record.url?scp=0034083234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034083234&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1097-4598(200006)23:6<979::AID-MUS23>3.0.CO;2-0

DO - 10.1002/(SICI)1097-4598(200006)23:6<979::AID-MUS23>3.0.CO;2-0

M3 - Article

C2 - 10842280

AN - SCOPUS:0034083234

VL - 23

SP - 979

EP - 983

JO - Muscle and Nerve

JF - Muscle and Nerve

SN - 0148-639X

IS - 6

ER -