Fructosamine reference ranges in rhesus macaques (Macaca mulatta)

Misty J. Williams-Fritze, Peter C. Smith, Daniel Zelterman, Jodi A. Carlson Scholz

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Naturally occurring diabetes mellitus (DM) is common in several species of Old and New World nonhuman primates. Fructosamine values provide important information about recent glycemic control and can be useful in the diagnosis and management of DM. However, despite an abundance of reports in the literature describing spontaneous and induced DM in monkeys, few reference ranges are available for fructosamine. Reference ranges have been published for woolly monkeys (Lagothrix lagotricha), cynomolgus macaques (Macaca fascicularis), and stumptail macaques (Macaca arctoides) but currently are not available for rhesus macaques. At our institution, DM is a common diagnosis in aging rhesus macaques. Here we report a reference range for fructosamine in rhesus macaques. The overall range was 157 to 230 H μmol/L, with male rhesus and macaques 10 y or older having significantly higher values than do female rhesus and macaques younger than 10 y, respectively. This range provides clinical veterinarians with an additional tool for evaluating glycemic control in rhesus macaques.

Original languageEnglish (US)
Pages (from-to)462-465
Number of pages4
JournalJournal of the American Association for Laboratory Animal Science
Volume50
Issue number4
StatePublished - Jul 1 2011

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ASJC Scopus subject areas

  • Animal Science and Zoology

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