Abstract
Frontotemporal lobar degeneration (FTLD) is the second most common cause of early-onset dementia. Major symptoms include behavioral disturbances and language impairment. Diagnosis relies upon clinical examination and brain imaging, showing evidence of frontotemporal involvement. Pathologically, there is frontotemporal atrophy, neuronal loss, and gliosis. FTLD carries a poor prognosis, with a median 3-year survival from diagnosis.
Original language | English (US) |
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Title of host publication | Encyclopedia of Movement Disorders |
Publisher | Elsevier Inc. |
Pages | 506-513 |
Number of pages | 8 |
ISBN (Electronic) | 9780123741059 |
ISBN (Print) | 9780123741011 |
DOIs | |
State | Published - Jan 1 2010 |
Keywords
- FTD
- FTDP-17
- FTLD
- Frontotemporal dementia
- MAPT
- PGRN
- Parkinsonism
ASJC Scopus subject areas
- General Medicine
- General Neuroscience