Frontotemporal Dementia-Parkinsonism

C. W. Wider, Zbigniew K Wszolek

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Frontotemporal lobar degeneration (FTLD) is the second most common cause of early-onset dementia. Major symptoms include behavioral disturbances and language impairment. Diagnosis relies upon clinical examination and brain imaging, showing evidence of frontotemporal involvement. Pathologically, there is frontotemporal atrophy, neuronal loss, and gliosis. FTLD carries a poor prognosis, with a median 3-year survival from diagnosis.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Movement Disorders
PublisherElsevier Inc.
Pages506-513
Number of pages8
ISBN (Electronic)9780123741059
ISBN (Print)9780123741011
DOIs
StatePublished - Jan 1 2010

Keywords

  • Frontotemporal dementia
  • FTD
  • FTDP-17
  • FTLD
  • MAPT
  • Parkinsonism
  • PGRN

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

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