Frequency of cytokine polymorphisms in populations from Western Europe, Africa, Asia, the Middle East and South America

Ashley Meenagh, Fionnuala Williams, Owen A. Ross, Chris Patterson, Clara Gorodezky, Mike Hammond, William A. Leheny, Derek Middleton

Research output: Contribution to journalArticle

139 Scopus citations

Abstract

PCR-SSOP identification procedures for IL-2, IL-6, IL-10, TNF-α and TNF-β cytokine polymorphisms have been developed. Application of the procedures to a range of diverse geographically distributed populations has identified ethnic differences within the groups studied. Five populations were investigated, Northern Ireland, South African Zulu, Omani, Singapore Chinese and Mexican Mestizos.

Original languageEnglish (US)
Pages (from-to)1055-1061
Number of pages7
JournalHuman Immunology
Volume63
Issue number11
DOIs
StatePublished - Nov 1 2002

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Keywords

  • Cytokine
  • PCR-SSOP
  • Populations
  • SNP

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Meenagh, A., Williams, F., Ross, O. A., Patterson, C., Gorodezky, C., Hammond, M., Leheny, W. A., & Middleton, D. (2002). Frequency of cytokine polymorphisms in populations from Western Europe, Africa, Asia, the Middle East and South America. Human Immunology, 63(11), 1055-1061. https://doi.org/10.1016/S0198-8859(02)00440-8